Evidence map›Paper›PMID 40427509›Full record

ArticleBiomolecules2025

Pancreatic MicroRNAs in

Olawale O Taiwo, Saif Rehman, Kenneth B Storey

Abstract read
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Olawale O TaiwoDepartment of Biology, Carleton University, Ottawa, ON K1S 5B6, Canada.ORCID 0009-0006-1358-7324
Saif RehmanDepartment of Biology, Carleton University, Ottawa, ON K1S 5B6, Canada.ORCID 0009-0006-0659-9896
Kenneth B StoreyDepartment of Biology, Carleton University, Ottawa, ON K1S 5B6, Canada.

Funding

Natural Sciences and Engineering Research Council RGPIN-2020-04733
6 · The paper itself

Abstract

Hibernation involves a profound metabolic rate depression (MRD) that enables certain species to survive prolonged periods of low energy availability. The thirteen-lined ground squirrel uses MRD to arrange cellular and biochemical pathways which suppress nonvital genetic and cellular pathways to conserve internal energy while preserving all essential processes. This study investigates the role of microRNAs (miRNAs) in controlling key signaling pathways and cellular processes in pancreatic tissue during hibernation. Using next-generation sequencing and broad genomic analysis, we analyzed and identified seven differentially expressed miRNAs (miR-29a-3p, miR-22-3p, miR-125-5p, miR-200a-3p, miR-328-3p, miR-21-5p, and miR-148-3p) in the pancreas of hibernating 13-lined ground squirrels (

Indexed as

Metabolic DiseasesMicroRNAsPancreasSciuridaeAnimalsBiomarkersGene Expression RegulationHibernationBiomarkersMicroRNAsglucose homeostasishibernationmetabolic diseasemetabolic rate suppressionmicroRNApancreatic tissue

Identifiers

PMID40427509
PMCPMC12109365

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.