Evidence map›Paper›PMID 40427594›Full record

ReviewBiomolecules2025

Molecular and Biophysical Perspectives on Dormancy Breaking: Lessons from Yeast Spore.

Keiichiro Sakai, Yohei Kondo, Kazuhiro Aoki, Yuhei Goto

Abstract readReview
In one paragraph

Review in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Keiichiro SakaiDepartment of Biology, Brooklyn College, The City University of New York, 2900 Bedford Avenue, Brooklyn, NY 11210, USA.ORCID 0000-0001-6669-7777
Yohei KondoCenter for One Medicine Innovative Translational Research (COMIT), Nagoya University, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.
Kazuhiro AokiLaboratory of Cell Cycle Regulation, Graduate School of Biostudies, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.
Yuhei GotoLaboratory of Cell Cycle Regulation, Graduate School of Biostudies, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.ORCID 0000-0002-5597-158X

Funding

Japan Science and Technology Agency JPMJAX22B8Japan Society for the Promotion of Science 18H02444Japan Society for the Promotion of Science 19H05675Japan Society for the Promotion of Science 19H05798Japan Society for the Promotion of Science 19K16050Japan Society for the Promotion of Science 22H02625Japan Society for the Promotion of Science 22J10844Japan Society for the Promotion of Science 22K15110
6 · The paper itself

Abstract

Dormancy is a physiological state that enables cells to survive under adverse conditions by halting their proliferation while retaining the capacity to resume growth when conditions become favorable. This remarkable transition between dormant and proliferative states occurs across a wide range of species, including bacteria, fungi, plants, and tardigrades. Among these organisms, yeast cells have emerged as powerful model systems for elucidating the molecular and biophysical principles governing dormancy and dormancy breaking. In this review, we provide a comprehensive summary of current knowledge on the molecular mechanisms underlying cellular dormancy, with particular focus on the two major model yeasts:

Indexed as

Saccharomyces cerevisiaeSchizosaccharomycesSpores, FungalGene Expression Regulation, FungalProteomeProteomicsProteomebudding yeastcytoplasmic fluiditydormancydormancy breakingfission yeastgerminationspore

Identifiers

PMID40427594
PMCPMC12109108

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.