Evidence map›Paper›PMID 40428329›Full record

ArticleGenes2025

Genetic Insights into Severe Obesity: A Case Study of

Altynay Imangaliyeva, Nurgul Sikhayeva, Aidos Bolatov, Talgat Utupov, Aliya Romanova, Ilyas Akhmetollayev, Elena Zholdybayeva

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Rare TruncatingGenes · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Altynay ImangaliyevaSchool of Medicine, Astana Medical University, Astana 010000, Kazakhstan.
Nurgul Sikhayeva"National Center for Biotechnology" LLP, JSC National Holding "Qazbiopharm", Korgalzhyn 13/1, Astana 010000, Kazakhstan.ORCID 0000-0001-6419-9483
Aidos BolatovSchool of Medicine, Astana Medical University, Astana 010000, Kazakhstan.ORCID 0000-0002-5390-4623
Talgat Utupov"National Center for Biotechnology" LLP, JSC National Holding "Qazbiopharm", Korgalzhyn 13/1, Astana 010000, Kazakhstan.
Aliya Romanova"National Center for Biotechnology" LLP, JSC National Holding "Qazbiopharm", Korgalzhyn 13/1, Astana 010000, Kazakhstan.
Ilyas Akhmetollayev"National Center for Biotechnology" LLP, JSC National Holding "Qazbiopharm", Korgalzhyn 13/1, Astana 010000, Kazakhstan.
Elena Zholdybayeva"National Center for Biotechnology" LLP, JSC National Holding "Qazbiopharm", Korgalzhyn 13/1, Astana 010000, Kazakhstan.ORCID 0000-0002-9677-008X

Funding

the Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan AP09057948
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Obesity, MorbidReceptor, Melanocortin, Type 4Body Mass IndexExome SequencingHumansMaleMutationPedigreePhenotypeYoung AdultMC4R protein, humanReceptor, Melanocortin, Type 4BMI heritabilityKazakh familymutationssevere obesitywhole-exome sequencing

Identifiers

PMID40428329
PMCPMC12111737

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.