Evidence map›Paper›PMID 40428370›Full record

ArticleGenes2025

Phylogenomic and Evolutionary Insights into Lipoprotein Lipase (LPL) Genes in Tambaqui: Gene Duplication, Tissue-Specific Expression and Physiological Implications.

Rômulo Veiga Paixão, Izabel Correa Bandeira, Vanessa Ribeiro Reis, Gilvan Ferreira da Silva, Fernanda Loureiro de Almeida O'Sullivan, Eduardo Sousa Varela

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rômulo Veiga PaixãoInstituto Federal de Educação, Ciência e Tecnologia do Amazonas (IFAM), Campus Presidente Figueiredo, Av. da Onça-Pintada, S/N-Galo da Serra, Presidente Figueiredo CEP 69735-000, AM, Brazil.ORCID 0000-0002-7242-7391
Izabel Correa BandeiraEmbrapa Amazônia Ocidental, Rodovia AM-010, Km 29, Caixa Postal 319, Manaus CEP 69010-790, AM, Brazil.ORCID 0000-0003-4411-1768
Vanessa Ribeiro ReisEmbrapa Amazônia Ocidental, Rodovia AM-010, Km 29, Caixa Postal 319, Manaus CEP 69010-790, AM, Brazil.
Gilvan Ferreira da SilvaEmbrapa Amazônia Ocidental, Rodovia AM-010, Km 29, Caixa Postal 319, Manaus CEP 69010-790, AM, Brazil.
Fernanda Loureiro de Almeida O'SullivanEmbrapa Pesca e Aquicultura, Palmas, TO, Brazil, Av. NS 10, Cruzamento com a Av. LO 18 Sentido Norte Loteamento-Água Fria, Palmas CEP 77008-900, TO, Brazil.ORCID 0000-0003-3507-2808
Eduardo Sousa VarelaEmbrapa Pesca e Aquicultura, Palmas, TO, Brazil, Av. NS 10, Cruzamento com a Av. LO 18 Sentido Norte Loteamento-Água Fria, Palmas CEP 77008-900, TO, Brazil.ORCID 0000-0003-0424-2683

Funding

CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico 443875/2024-3FAPEAM - Fundação de Amparo a Pesquisa do Estado do Amazonas 01.02.016301.00449/2022-25
6 · The paper itself

Abstract

BACKGROUND/

objectivesLipoprotein lipase (LPL) is a key enzyme in lipid metabolism, crucial for the hydrolysis of triglycerides in lipoproteins and maintaining lipid homeostasis in vertebrates. This study aims to characterize the lipoprotein lipase genes in the tambaqui (

methodsPhylogenetic and syntenic analyses were used to identify the

resultsWe identified three

conclusionsThis study offers new insights into the evolution and functional diversification of lipoprotein lipases in vertebrates, highlighting the complexity of lipid metabolism in fish. These findings contribute to understanding the adaptability of teleost fish to diverse environments and lay the foundation for future research in lipid metabolism regulation, including Neotropical species, with potential applications in aquaculture and conservation.

Indexed as

Fish ProteinsGene DuplicationLipoprotein LipaseAnimalsEvolution, MolecularGenomeLipid MetabolismOrgan SpecificityPhylogenyFish ProteinsLipoprotein Lipasecomparative genomicsgene duplicationgene expressionlipaselipid metabolismlipoproteinsneotropical fish

Identifiers

PMID40428370
PMCPMC12111056

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.