Evidence mapPaperPMID 40428463Full record

ReviewFoods (Basel, Switzerland)2025

Advancements in the Extraction, Characterization, and Bioactive Potential of Laminaran: A Review.

Kit-Leong Cheong, Amanullah Sabir, Min Wang, Saiyi Zhong, Karsoon Tan

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kit-Leong CheongGuangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.ORCID 0000-0001-8380-0123
Amanullah SabirGuangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Min WangCollege of Coastal Agriculture Sciences, Guangdong Ocean University, Zhanjiang 524088, China.ORCID 0009-0009-8866-6547
Saiyi ZhongGuangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Karsoon TanGuangxi Key Laboratory of Beibu Gulf Biodiversity Conservation, Beibu Gulf University, Qinzhou 535011, China.ORCID 0009-0006-1489-7842

Funding

Key Research Project of High Education of Guangdong Province 2024ZDZX2084Natural Science Foundation of Guangdong Province 2025A1515010078
6 · The paper itself

Abstract

Laminaran, a bioactive β-glucan derived from brown algae, has garnered significant attention due to its diverse pharmacological properties, including antioxidant, immunomodulatory, and mucosal protective effects. Despite promising research highlighting its potential applications in functional foods, nutraceuticals, and pharmaceuticals, the commercial utilization of laminaran remains limited, primarily due to challenges in extraction efficiency, structural complexity, and a lack of standardized methodologies. This review critically examines recent advancements in the extraction, purification, structural characterization, and biological evaluation of laminaran. Both conventional and emerging extraction methods-including ultrasound-assisted extraction, microwave-assisted extraction, and enzymatic techniques-are evaluated for their efficiency, scalability, and sustainability. Analytical tools, such as high-performance liquid chromatography, nuclear magnetic resonance, and mass spectrometry, are discussed for their roles in elucidating key structural features, such as molecular weight, degree of polymerization, and glycosidic linkage patterns, which are closely tied to laminaran's biological activity. Innovative extraction technologies have improved yield and purity, while structural insights have deepened the understanding of structure-function relationships. Interdisciplinary collaboration will be critical to advance laminaran from a marine-derived polysaccharide to a commercially viable bioactive compound for health, nutrition, and biomaterial applications.

Indexed as

characterizationextractionlaminaranmucosal barrierpurification

Identifiers

PMID40428463
PMCPMC12110979

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.