Evidence map›Paper›PMID 40429741›Full record

ArticleInternational journal of molecular sciences2025

Reduced Sulfur Diet Reshapes the Microbiome and Metabolome in Mild-Moderate Ulcerative Colitis.

Jiayu Ye, Maitreyi Raman, Lorian M Taylor, Munazza Yousuf, Remo Panaccione, Christian Turbide, Sidhartha R Sinha, Natasha Haskey

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiayu YeDivision of Gastroenterology and Hepatology, Stanford Medicine, Stanford University, 300 Pasteur Dr., Palo Alto, CA 94305, USA.ORCID 0000-0002-1704-6780
Maitreyi RamanDepartment of Medicine, Cumming School of Medicine, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada.ORCID 0000-0002-9129-3632
Lorian M TaylorDepartment of Medicine, Cumming School of Medicine, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada.
Munazza YousufDepartment of Medicine, Cumming School of Medicine, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada.
Remo PanaccioneDepartment of Medicine, Cumming School of Medicine, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada.
Christian TurbideDepartment of Medicine, Cumming School of Medicine, University of Calgary, 2500 University Drive NW, Calgary, AB T2N 1N4, Canada.
Sidhartha R SinhaDivision of Gastroenterology and Hepatology, Stanford Medicine, Stanford University, 300 Pasteur Dr., Palo Alto, CA 94305, USA.ORCID 0000-0001-5104-6410
Natasha HaskeyDepartment of Biology, Irving K Barber Faculty of Science, University of British Columbia-Okanagan, 3187 University Way, Kelowna, BC V1V 1V7, Canada.ORCID 0000-0001-7349-9445

Funding

Alberta's Collaboration of Excellence for Nutrition in Digestive Diseases (Ascend), Cumming School of Medicine, University of Calgary, Calgary, Canada NAMichael Smith Health Research BC Health Professional Investigator Award NANutricia North America NATRIANGLE (TRaIning A New generation of researchers in Gastroenterology and LivEr) Fellowship Award NA
6 · The paper itself

Abstract

This pilot study investigated the effects of a reduced sulfur (RS) diet on the gut microbiome composition and fecal metabolome in individuals with remitted or active ulcerative colitis (UC). Thirteen participants maintained their habitual diet (control), while nine followed an RS diet for eight weeks (Wk8). Stool and plasma samples were collected at the baseline and Wk8. The sulfur intake decreased in the RS group (-28 g/1000 kcal) versus the control group (-1.7 g/1000 kcal;

Indexed as

Colitis, UlcerativeDietGastrointestinal MicrobiomeMetabolomeSulfurAdultFecesFemaleHumansMaleMiddle AgedPilot ProjectsSulfurreduced sulfur dietsulfitessulfursulfur metabolites

Identifiers

PMID40429741
PMCPMC12111015

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.