Evidence map›Paper›PMID 40429746›Full record

ArticleInternational journal of molecular sciences2025

Deciphering the Transcriptomic Complexity of Yak Skin Across Different Ages and Body Sites.

Xiaolan Zhang, Bingang Shi, Zhidong Zhao, Yunqi Deng, Xuelan Zhou, Jiang Hu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaolan ZhangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Bingang ShiCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Zhidong ZhaoCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.ORCID 0000-0003-4672-7873
Yunqi DengCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.ORCID 0009-0000-7965-2893
Xuelan ZhouCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.
Jiang HuCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China.

Funding

Gansu Agricultural University GAU-DK-QNJJ-202302
6 · The paper itself

Abstract

Differences in skin and hair phenotypes between the scapular and ventral regions of yaks (Bos grunniens) are obvious and become more prominent with age. However, the genetic mechanism that causes differences in yak skin at different ages has not been reported. In this study, we investigated the transcriptomic profile of yak skin across different ages (0.5 years, 2.5 years, and 4.5 years) and body sites (scapular and ventral regions). Differential gene expression analysis was initially conducted to explore the transcriptomic differences in skin at different ages and different body sites. Subsequently, weighted gene co-expression network analysis (WGCNA) was employed to analyze the transcriptomic data comprehensively. The results showed that, among all comparison groups, the Y2.5_S vs. Y2.5_V group (regional comparison) exhibited the highest number of DEGs, with 491 genes (179 upregulated and 312 downregulated), followed by the Y2.5_V vs. Y0.5_V group (age comparison), which had 370 DEGs (103 upregulated and 267 downregulated). DEGs such as

Indexed as

AgingSkinTranscriptomeAge FactorsAnimalsCattleGene Expression ProfilingGene Regulatory Networksagesskin transcriptomeWGCNAyak

Identifiers

PMID40429746
PMCPMC12111109

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.