Evidence mapPaperPMID 40429784Full record

ArticleInternational journal of molecular sciences2025

A New Bromelain-Based Polyenzymatic Complex Plus N-Acetylcysteine: A Promising Approach for the Treatment of Urinary Tract Infections.

Lucia Recinella, Morena Pinti, Silvia Di Lodovico, Andrea Brenciani, Eleonora Giovanetti, Firas Diban, Mara Di Giulio, Luigi Brunetti, Sheila Leone

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lucia RecinellaDepartment of Pharmacy, "G. d'Annunzio" University, 66100 Chieti, Italy.
Morena PintiDepartment of Pharmacy, "G. d'Annunzio" University, 66100 Chieti, Italy.ORCID 0009-0002-2037-1063
Silvia Di LodovicoDepartment of Pharmacy, "G. d'Annunzio" University, 66100 Chieti, Italy.ORCID 0000-0001-9281-5028
Andrea BrencianiDepartment of Biomedical Sciences and Public Health, Polytechnic University of Marche, 60020 Ancona, Italy.ORCID 0000-0001-5191-3908
Eleonora GiovanettiDepartment of Life and Environmental Sciences, Polytechnic University of Marche, 60131 Ancona, Italy.ORCID 0000-0002-9427-8091
Firas DibanDepartment of Pharmacy, "G. d'Annunzio" University, 66100 Chieti, Italy.ORCID 0000-0003-1509-6087
Mara Di GiulioDepartment of Pharmacy, "G. d'Annunzio" University, 66100 Chieti, Italy.ORCID 0000-0002-8375-9404
Luigi BrunettiDepartment of Pharmacy, "G. d'Annunzio" University, 66100 Chieti, Italy.
Sheila LeoneDepartment of Pharmacy, "G. d'Annunzio" University, 66100 Chieti, Italy.ORCID 0000-0003-1291-550X

Funding

Difass International Spa Difass International Spa 2024
6 · The paper itself

Abstract

Biofilm plays a crucial role in the pathogenesis and chronicity of urinary tract infections (UTIs). The present work aimed to evaluate the anti-biofilm effects of Formulation (DIF17BRO

Indexed as

AcetylcysteineAnti-Bacterial AgentsBromelainsUrinary Tract InfectionsAnimalsBiofilmsCiprofloxacinEscherichia coliHumansMicrobial Sensitivity TestsMothsAcetylcysteineAnti-Bacterial AgentsBromelainsCiprofloxacinbiofilmbromelainEscherichia coliN-acetylcysteineurinary infections

Identifiers

PMID40429784
PMCPMC12111221

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.