Evidence map›Paper›PMID 40430153›Full record

ArticleLife (Basel, Switzerland)2025

An Advanced Pneumatic Compression Therapy System Improves Leg Volume and Fluid, Adipose Tissue Thickness, Symptoms, and Quality of Life and Reduces Risk of Lymphedema in Women with Lipedema.

Karen L Herbst, Carlos Zelaya, Marianne Sommerville, Tatiana Zimmerman, Lindy McHutchison

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karen L HerbstThe Roxbury Institute, Tucson, AZ 85715, USA.ORCID 0000-0002-9079-9754
Carlos ZelayaCarolina Vein Center, Durham, NC 27713, USA.
Marianne SommervilleCarolina Vein Center, Durham, NC 27713, USA.
Tatiana ZimmermanCarolina Vein Center, Durham, NC 27713, USA.
Lindy McHutchisonCarolina Vein Center, Durham, NC 27713, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipedema is a painful disease of subcutaneous adipose tissue (SAT) in women. This study determined whether an advanced pneumatic compression device (APCD) improved lipedema SAT depth, swelling, and pain. Women with lipedema started 20-30 mm Hg compression leggings then were randomized to an APCD (Lympha Press Optimal Plus) group for 30 days (treatment; n = 22) or a no APCD (Control; n = 24) group. APCD treatment significantly reduced left leg volume (3D imaging, LymphaTech;

Indexed as

advanced pneumatic compression devicebioimpedance spectroscopycompression therapyextracellular fluidintracellular fluidlipedemalymphedemaultrasound

Identifiers

PMID40430153
PMCPMC12113227

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.