Evidence mapPaperPMID 40430451Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Effects of Carnosine Supplementation on Cognitive Outcomes in Prediabetes and Well-Controlled Type 2 Diabetes: A Randomised Placebo-Controlled Clinical Trial.

Rohit Hariharan, Aya Mousa, Kirthi Menon, Jack Feehan, Barbara Ukropcová, Jozef Ukropec, Martin Schön, Arshad Majid, Giancarlo Aldini, Maximilian de Courten and 3 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rohit HariharanMonash Centre for Health Research Implementation, Faculty of Medicine, Nursing and Health Sciences, Monash University, 43-51 Kanooka Grove, Clayton, VIC 3168, Australia.ORCID 0000-0003-4273-3205
Aya MousaMonash Centre for Health Research Implementation, Faculty of Medicine, Nursing and Health Sciences, Monash University, 43-51 Kanooka Grove, Clayton, VIC 3168, Australia.ORCID 0000-0002-7356-4523
Kirthi MenonMonash Centre for Health Research Implementation, Faculty of Medicine, Nursing and Health Sciences, Monash University, 43-51 Kanooka Grove, Clayton, VIC 3168, Australia.
Jack FeehanSchool of Health and Biomedical Sciences, STEM College, RMIT University, 30 Janefield Drive, Bundoora, VIC 3083, Australia.ORCID 0000-0002-9627-1299
Barbara UkropcováDepartment of Metabolic Disease Research, Institute of Experimental Endocrinology, Biomedical Research Centre, Slovak Academy of Sciences, Dúbravská Cesta 9, 845 05 Bratislava, Slovakia.
Jozef UkropecDepartment of Metabolic Disease Research, Institute of Experimental Endocrinology, Biomedical Research Centre, Slovak Academy of Sciences, Dúbravská Cesta 9, 845 05 Bratislava, Slovakia.ORCID 0000-0001-8401-6621
Martin SchönDivision of Endocrinology and Diabetology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Moorenstraße 5 Universitätsklinikum, 40225 Düsseldorf, Germany.
Arshad MajidSheffield Institute for Translational Neuroscience, School of Medicine and Population Health, University of Sheffield, 385a Glossop Rd, Sheffield S10 2HQ, UK.
Giancarlo AldiniDepartment of Pharmaceutical Sciences, University of Milan, Via Luigi Mangiagalli, 25, 20133 Milan, Italy.ORCID 0000-0002-2355-6744
Maximilian de CourtenInstitute of Health and Sport, Victoria University, 70/104 Ballarat Rd, Footscray, VIC 3011, Australia.ORCID 0000-0001-9997-9359
James CameronDepartment of Medicine, School of Clinical Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, 246 Clayton Road, Clayton, VIC 3168, Australia.ORCID 0000-0003-0589-0367
Simon M BellSheffield Institute for Translational Neuroscience, School of Medicine and Population Health, University of Sheffield, 385a Glossop Rd, Sheffield S10 2HQ, UK.ORCID 0000-0002-2781-6478
Barbora de CourtenDepartment of Medicine, School of Clinical Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, 246 Clayton Road, Clayton, VIC 3168, Australia.ORCID 0000-0001-8760-2511

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antioxidants and cognitive functionCANTAB cognitive testingcarnosine supplementationcognition and diabetescognitive functiondiabetes and neurodegenerationexecutive function and diabetesinflammation and cognitive declineinsulin resistance and cognitionmetabolic health and cognitionneurocognitive outcomesneuropsychological assessmentprediabetes and cognitionrandomised controlled trial (RCT)type 2 diabetes

Identifiers

PMID40430451
PMCPMC12114902

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.