Evidence map›Paper›PMID 40431193›Full record

ReviewMicroorganisms2025

Probiotic Fermentation of Defatted Cottonseed Meal for Sustainable Foods and Non-Food Applications.

Zhanqiang Yan, Tian Li, Gen Zou, Xiaoling Zhang, Lingbo Qu, Yongjun Wei

Abstract readReview
In one paragraph

Review in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. A Marine Alkaline Protease fromMicroorganisms · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhanqiang YanSchool of Medicine, Huanghe Science & Technology University, School of Chemical Engineering, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Tian LiSchool of Medicine, Huanghe Science & Technology University, School of Chemical Engineering, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Gen ZouInstitute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Southern Key Laboratory of Edible Fungus Resource Utilization, Ministry of Agriculture, National Engineering Research Center of Edible Fungi, Shanghai 201403, China.ORCID 0000-0001-5574-1824
Xiaoling ZhangSchool of Medicine, Huanghe Science & Technology University, School of Chemical Engineering, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Lingbo QuSchool of Medicine, Huanghe Science & Technology University, School of Chemical Engineering, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Yongjun WeiSchool of Medicine, Huanghe Science & Technology University, School of Chemical Engineering, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0002-1554-1999

Funding

Henan Province Outstanding Youth Foundation 242300421097
6 · The paper itself

Abstract

Cottonseed is a valuable source of high-quality proteins and oils. Defatted cottonseed meal (DCSM), a by-product of cottonseed oil extraction, holds significant potential as a sustainable protein resource. This review outlines the chemical composition, structural features, and unique properties of cottonseed, with a focus on its inherent antinutritional factors, such as gossypol. Strategies for enhancing the utilization of DCSM as a protein source are systematically evaluated, including physical, chemical, and biological methods used to eliminate or reduce antinutritional components. Among these, microbial fermentation, particularly solid-state fermentation, is highlighted as a promising, eco-friendly approach for detoxification and nutritional improvement. This review further discusses critical factors influencing the removal of anti-nutritional compounds, such as pretreatment methods, fermentation parameters, and microbial strains. The efficacy of probiotic strains (e.g.,

Indexed as

cottonseedsgossypol removalplant proteinprobiotic fermentationsolid-state fermentation

Identifiers

PMID40431193
PMCPMC12114460

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.