Evidence map›Paper›PMID 40431663›Full record

ArticleViruses2025

Genotypic Characterization of Human Respiratory Syncytial Viruses Detected in Mexico Between 2021 and 2024.

Nadia Martínez-Marrero, Juan Carlos Muñoz-Escalante, Rosa Maria Wong-Chew, Pedro Torres-González, Miguel Leonardo García-León, Patricia Bautista-Carbajal, Pedro Antonio Martínez-Arce, María Del Carmen Espinosa-Sotero, Verónica Tabla-Orozco, Fabian Rojas-Larios and 4 more

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nadia Martínez-MarreroInfectious Diseases Laboratory, Centro de Investigación en Ciencias de la Salud y Biomedicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78210, Mexico.ORCID 0009-0009-9062-2631
Juan Carlos Muñoz-EscalanteInfectious Diseases Laboratory, Centro de Investigación en Ciencias de la Salud y Biomedicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78210, Mexico.ORCID 0000-0002-7284-0194
Rosa Maria Wong-ChewInfectious Diseases Research Laboratory, Research Division, Facultad de Medicina, Universidad Nacional Autónoma de Mexico, Ciudad de Mexico 04510, Mexico.ORCID 0000-0002-3582-5120
Pedro Torres-GonzálezInfectious Diseases Laboratory, Centro de Investigación en Ciencias de la Salud y Biomedicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78210, Mexico.
Miguel Leonardo García-LeónInfectious Diseases Research Laboratory, Research Division, Facultad de Medicina, Universidad Nacional Autónoma de Mexico, Ciudad de Mexico 04510, Mexico.
Patricia Bautista-CarbajalInfectious Diseases Research Laboratory, Research Division, Facultad de Medicina, Universidad Nacional Autónoma de Mexico, Ciudad de Mexico 04510, Mexico.ORCID 0000-0003-1641-127X
Pedro Antonio Martínez-ArceHospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara 44280, Mexico.
María Del Carmen Espinosa-SoteroHospital General de Mexico "Dr. Eduardo Liceaga", Ciudad de Mexico 06720, Mexico.ORCID 0009-0003-1315-1246
Verónica Tabla-OrozcoHospital Pediátrico de Coyoacán, Ciudad de Mexico 04100, Mexico.
Fabian Rojas-LariosHospital Regional Universitario de los Servicios de Salud de Colima, Colima 28010, Mexico.ORCID 0000-0003-1744-9173
Susana Juárez-TobíasHospital Central "Dr. Ignacio Morones Prieto", San Luis Potosí 78210, Mexico.
Ana María González-OrtizHospital del Niño y la Mujer "Dr. Alberto López Hermosa", San Luis Potosí 78364, Mexico.ORCID 0000-0002-7762-2882
Ángel Gabriel Alpuche-SolísLaboratorio de Biología Molecular de Plantas, División de Biología Molecular, Instituto Potosino de Investigación Científica y Tecnológica A.C., San Luis Potosí 78216, Mexico.ORCID 0000-0002-3342-0365
Daniel E NoyolaInfectious Diseases Laboratory, Centro de Investigación en Ciencias de la Salud y Biomedicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78210, Mexico.ORCID 0000-0002-4840-6742

Funding

CONACYT-PRONACES 303081 (Proyecto "Infecciones virales de las vías respiratorias")
6 · The paper itself

Abstract

Human respiratory syncytial virus (HRSV) is a leading cause of severe respiratory infections among children, older adults, and immunocompromised individuals. The COVID-19 pandemic and the non-pharmacological interventions to mitigate it resulted in significant changes in HRSV epidemiology and seasonality patterns. Worldwide, there was a considerable reduction in the number of HRSV infections during that period, and the impact of those changes on genotype distribution is still not fully understood. In this work, we analyzed the genotypic characteristics of HRSV strains detected between 2021 and 2024 in Mexico with the aim of identifying changes in circulating lineages. HRSV positive samples collected in five states in Mexico were used. The complete viral attachment glycoprotein gene was sequenced, and phylogenetic inference was performed using datasets including all sequences available at GenBank and GISAID until 30 June 2024. We obtained 114 HRSV sequences (63.2% HRSV-A and 36.8% HRSV-B); 19 were from the 2021-2022 season, 53 from 2022-2023, and 42 from 2023-2024. All HRSV-A sequences clustered with sequences from other countries within A.D lineages, including A.D.1, A.D.3, A.D.5.1, and A.D.5.2 lineages. All HRSV-B sequences clustered in the B.D.E.1 lineage with sequences collected between 2020 and 2024. In conclusion, the characterization of HRSV viruses circulating in Mexico during and after the SARS-CoV-2 pandemic and comparison to all available sequences reported to date corroborates that, on a global scale, HRSV-A viruses of several A.D lineages circulate simultaneously, while HRSV-B viruses are restricted to the B.D.E.1 lineage.

Indexed as

GenotypeRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAdolescentAdultChildChild, PreschoolCOVID-19FemaleHumansInfantMaleMexicoMiddle AgedPhylogenySeasonsacute respiratory infectionsgenotypemolecular epidemiologypneumovirusrespiratory syncytial virus

Identifiers

PMID40431663
PMCPMC12115737

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.