Evidence mapPaperPMID 40432425Full record

SynthesisPsychological medicine2025

The association between disordered eating and psychosis in clinical and non-clinical populations: a systematic review and meta-analysis.

Georgia Drymonitou, Amy McCulloch, Sarah Parry, Rhia Gough, Rodrigo Moreira Cruz, Mia Mostoufi, Mariam Jawad, Charlotte Newman, Duncan Harding, Gonzalo Salazar de Pablo and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Georgia DrymonitouOxford Health NHS Foundation Trust, Oxford, UK.
Amy McCullochDivision of Psychology & Mental Health, University of Manchester, Manchester, UK.
Sarah ParryDivision of Psychology & Mental Health, University of Manchester, Manchester, UK.
Rhia GoughFlorence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, UK.
Rodrigo Moreira CruzFlorence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, UK.
Mia MostoufiNorth East London NHS Foundation Trust, London, UK.
Mariam JawadSouth London and Maudsley NHS Foundation Trust, London, UK.
Charlotte NewmanDoctoral Programme in Clinical Psychology, University of Hertfordshire, Hatfield, UK.
Duncan HardingSouth London and Maudsley NHS Foundation Trust, London, UK.
Gonzalo Salazar de PabloDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Tom JewellFlorence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London, UK.ORCID 0000-0003-4084-7786

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEating disorders and psychotic disorders represent two of the most serious psychiatric conditions. Emerging lines of evidence from genetic and epidemiological studies suggest that these disorders may commonly co-occur. This systematic review investigated the association between these disorders across community and clinical populations.

methodA systematic review was preregistered (CRD42021231771) and conducted according to PRISMA guidelines. Web of Science, PsycINFO and Medline were searched for articles on the association and comorbidity between psychosis and eating disorders up to the 26th February 2024. A random effects meta-analysis was conducted for studies reporting comorbidity of eating disorders and psychotic disorders based on clinical diagnosis or interview measures, to estimate prevalence of the comorbidity between these disorders. A narrative synthesis was conducted for all other studies and grouped by sample (general population, eating disorders or psychotic disorders).

resultsIn total 43 studies met inclusion criteria for the systematic review and 16 were included in the meta-analysis. Findings suggest substantial comorbidity between eating disorders and psychotic disorders, with a pooled comorbidity prevalence of 8% (CI: 3, 14) based on clinical diagnosis or interview measures. Studies using self-report questionnaires also highlight the association between eating disorders and psychosis across clinical and community populations.

conclusionsEating disorders and psychotic disorders frequently co-occur. Further research should investigate the temporal order of symptom development and consider the need for novel interventions targeted at overlapping psychotic and eating disorder symptoms and associated phenomena.

Indexed as

Feeding and Eating DisordersPsychotic DisordersComorbidityHumansPrevalencedisordered eatingeating disordersmeta-analysisprevalencepsychosis

Identifiers

PMID40432425
PMCPMC12150339

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.