Evidence map›Paper›PMID 40433142›Full record

ReviewCJC open2025

Unraveling Heart Failure Phenotypes: A Systematic Review and Meta-analysis of Peak Oxygen Uptake and Its Determinants.

Corey R Tomczak, Stephen J Foulkes, Christopher Weinkauf, Devyn Walesiak, Jing Wang, Veronika Schmid, Sarah Paterson, Wesley J Tucker, Michael D Nelson, Simon Wernhart and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in CJC open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. CPET Characteristics in HFrEF, HFpEF and COPD.Journal of clinical medicine · 2026
    Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Corey R TomczakCollege of Kinesiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Stephen J FoulkesiCARE Laboratory, Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada.
Christopher WeinkaufiCARE Laboratory, Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada.
Devyn WalesiakiCARE Laboratory, Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada.
Jing WangDivision of Public Health, School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Veronika SchmidDepartment of Sports Medicine and Sports Cardiology, TUM University Hospital, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Sarah PatersoniCARE Laboratory, Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada.
Wesley J TuckerNutrition and Food Sciences, Texas Woman's University, Houston, Texas, USA.
Michael D NelsonCollege of Nursing and Health Innovation, University of Texas at Arlington, Arlington, Texas, USA.
Simon WernhartDepartment of Sports Medicine and Sports Cardiology, TUM University Hospital, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Jan VontobelHochgebirgsklinik, Medicine Campus Davos, Davos, Switzerland.
David NiederseerHochgebirgsklinik, Medicine Campus Davos, Davos, Switzerland.
Mark J HaykowskyiCARE Laboratory, Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Understanding the impact of heart failure (HF) phenotype on peak oxygen uptake (peak Methods: Studies comparing peak Results: After screening 3107 articles, 25 unique studies were included in the analysis for the primary outcome (HFrEF n = 3783; HFpEF n = 3279). Peak Conclusions: Our findings highlight distinct physiological impairments along the oxygen cascade in HFrEF compared with HFpEF, with direct implications for the management and treatment strategies of these HF subtypes.

Identifiers

PMID40433142
PMCPMC12105755

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.