ArticleClinical, cosmetic and investigational dentistry2025
Effects of Hyaluronic Acid Gel on Initial Wound Healing Following Tooth Extraction and Crown Lengthening Procedures: A Retrospective Analysis.
Article in Clinical, cosmetic and investigational dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Hyaluronic Acid-Based Gels and Biomaterial Systems for Oral Wound Healing: Design and Clinical Translation.Gels (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: There is limited evidence highlighting the implications of adjunctive topical application of wound healing agents on clinical and patient-related outcomes in surgical procedures. The aim of the retrospective analysis was to evaluate the effects of 0.8% hyaluronic acid (HA) gel on wound healing following tooth extraction and crown lengthening procedures using the Inflammatory Proliferative and Remodeling (IPR) scale in a postgraduate clinical setting. Methods: A retrospective assessment of medical record database related to clinical and patient-related outcomes of patients who received tooth extraction or crown lengthening procedures was conducted. Wound healing was assessed using the IPR scale providing scores for patient-reported postoperative pain, bleeding, granulation tissue, hematoma, tissue color compared to unaffected site, complete/incomplete flap closure, suppuration, and edema. The test group included participants who received an adjuvant application of 1mL of 0.8% HA gel Results: Overall, no statistically significant differences were observed between the total IPR wound healing scores for test (5.54 ±1.02) Conclusion: Although 0.8% HA gel did not significantly improve early wound healing, well-designed clinical trials are necessary to evaluate its safety and potential benefits in routine periodontal surgeries. The IPR wound healing index demonstrated high reliability with excellent inter- and intra-examiner agreement in assessing the initial healing process after periodontal surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.