Evidence map›Paper›PMID 40433995›Full record

ReviewHistology and histopathology2025

Ion channels and actin: A tale of two friends.

Federico Sesti, Elena Forzisi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Histology and histopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Federico SestiDepartment of Neuroscience and Cell Biology, Robert Wood Johnson Medical School, Rutgers University, NJ, USA. sestife@rwjms.rutgers.edu.
Elena ForzisiDepartment of Neuroscience and Cell Biology, Robert Wood Johnson Medical School, Rutgers University, NJ, USA.

Funding

NSF 2030348
6 · The paper itself

Abstract

An increasing number of studies highlight ion channels as multifunctional proteins involved in diverse cellular processes, including proliferation, differentiation, adhesion, migration, morphology, and programmed cell death (apoptosis). Given these broad roles, it is not surprising that ion channels interact closely with actin-a ubiquitous cytoskeletal component that participates in a vast array of biological functions. Ion channels depend on the actin cytoskeleton for essential activities such as trafficking to and from the plasma membrane. Conversely, actin dynamics are often modulated by ion channels during various cellular events. In this review, we provide an overview of the field and discuss key examples that reveal emerging patterns in the bidirectional interactions between ion channels and the actin cytoskeleton.

Indexed as

Actin CytoskeletonActinsIon ChannelsAnimalsCytoskeletonHumansActinsIon Channels

Identifiers

PMID40433995

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.