Evidence map›Paper›PMID 40434504›Full record

ReviewProbiotics and antimicrobial proteins2025

Harnessing Probiotics: Exploring the Role of the Gut Microbiome in Combating Obesity.

Riyasdeen Anvarbatcha, Faisal Kunnathodi, Amr A Arafat, Sarfuddin Azmi, Mohammad Mustafa, Ishtiaque Ahmad, Haifa F Alotaibi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Foods (Basel, Switzerland) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Riyasdeen AnvarbatchaHealth Research Center, Kingdom of Saudi Arabia, Ministry of Defense Health Services, Riyadh, Kingdom of Saudi Arabia.ORCID 0000-0002-5597-4684
Faisal KunnathodiHealth Research Center, Kingdom of Saudi Arabia, Ministry of Defense Health Services, Riyadh, Kingdom of Saudi Arabia.ORCID 0000-0002-5958-3672
Amr A ArafatHealth Research Center, Kingdom of Saudi Arabia, Ministry of Defense Health Services, Riyadh, Kingdom of Saudi Arabia.ORCID 0000-0003-0951-7287
Sarfuddin AzmiHealth Research Center, Kingdom of Saudi Arabia, Ministry of Defense Health Services, Riyadh, Kingdom of Saudi Arabia.ORCID 0000-0002-1868-3458
Mohammad MustafaHealth Research Center, Kingdom of Saudi Arabia, Ministry of Defense Health Services, Riyadh, Kingdom of Saudi Arabia.ORCID 0000-0001-6130-4225
Ishtiaque AhmadHealth Research Center, Kingdom of Saudi Arabia, Ministry of Defense Health Services, Riyadh, Kingdom of Saudi Arabia.ORCID 0009-0008-9303-7529
Haifa F AlotaibiHealth Research Center, Kingdom of Saudi Arabia, Ministry of Defense Health Services, Riyadh, Kingdom of Saudi Arabia. halotaibe@mod.gov.sa.ORCID 0000-0003-2266-7394

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity has become a global health crisis driven by genetic, environmental, and lifestyle factors, often linked to gut microbiome imbalances. Probiotics, particularly Lactobacillus and Bifidobacterium strains, have shown promise in clinical trials by promoting weight loss, improving lipid profiles, and addressing gut dysbiosis associated with obesity. This review surveys the literature on the microbiome and obesity, emphasizing the clinical relevance of probiotics in treatment strategies. Our comprehensive PubMed search highlights the mechanisms through which probiotics influence metabolic health, including their effects on inflammation and appetite regulation. We also explore promising future research directions and the potential for integrating probiotics into clinical practice. While results are encouraging, the evidence is limited by strain variability, small sample sizes, short trial durations, and individual differences in microbiota composition. More extensive, long-term studies with standardized methods are crucial to confirm the effectiveness of probiotics as viable anti-obesity treatments.

Indexed as

Gastrointestinal MicrobiomeObesityProbioticsAnimalsBifidobacteriumHumansBifidobacteriumGut microbiomeLactobacillusObesityProbiotics

Identifiers

PMID40434504

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.