Evidence map›Paper›PMID 40435037›Full record

ArticleEpidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil2025

COVID-19 case fatality ratio and survival among hospitalized adults in Goiás, 2020: a cohort study.

Moara Alves Santa Bárbara Borges, Ana Laura de Sene Amâncio Zara, Lísia Gomes Martins de Moura Tomich, Adriana Oliveira Guilarde, Cacilda Pedrosa de Oliveira, Deborah Lopes Mota Carvajal, Marina Mascarenhas Roriz Pedrosa, Paulo Sérgio Sucasas da Costa, Marília Dalva Turchi

Abstract read
In one paragraph

Article in Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Moara Alves Santa Bárbara BorgesUniversidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brazil.ORCID http://orcid.org/0000-0003-2461-2063
Ana Laura de Sene Amâncio ZaraUniversidade Federal de Goiás, Faculdade de Farmácia, Programa de Pós-Graduação de Assistência de Avaliação em Saúde, Goiânia, GO, Brazil.ORCID http://orcid.org/0000-0001-7012-9078
Lísia Gomes Martins de Moura TomichUniversidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brazil.ORCID http://orcid.org/0000-0003-0366-7487
Adriana Oliveira GuilardeUniversidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brazil.ORCID http://orcid.org/0000-0012-5032-8085
Cacilda Pedrosa de OliveiraUniversidade Federal de Goiás, Faculdade de Medicina, Departamento de Clínica Médica, Goiânia, GO, Brazil.ORCID http://orcid.org/0000-0002-7191-0322
Deborah Lopes Mota CarvajalUniversidade Evangélica de Goiás, Faculdade de Medicina, Anápolis, GO, Brazil.ORCID http://orcid.org/0000-0001-8862-9214
Marina Mascarenhas Roriz PedrosaHospital de Campanha para o Enfrentamento ao Coronavírus de Goiânia, Goiânia, GO, Brazil.ORCID http://orcid.org/0009-0004-7466-8596
Paulo Sérgio Sucasas da CostaUniversidade Federal de Goiás, Faculdade de Medicina, Departamento de Pediatria, Goiânia, GO, Brazil.ORCID http://orcid.org/0000-0001-9370-9139
Marília Dalva TurchiUniversidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia, GO, Brazil.ORCID http://orcid.org/0000-0001-5438-1345

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe clinical-epidemiological and therapeutic aspects and to estimate case fatality ratio and risk factors for lower in-hospital survival due to COVID-19.

methodsThis is a retrospective cohort study conducted in the state of Goiás, Brazil, in 2020, with data obtained from the Influenza Epidemiological Surveillance Information System and through a review of clinical records and hospital. Relative risk for in-hospital death was estimated and Poisson multiple regression and Cox regression analyses were performed. Survival functions were compared using the log-rank test and represented by Kaplan-Meier curves.

resultsThe sample consisted of 651 adults, whose median age was 59 years, 57.0% were admitted to public hospitals, 61.1% had severe acute respiratory syndrome on admission and 72.0% had at least one comorbidity, the most frequent being hypertension , diabetes and obesity. The overall case fatality ratio was 17.5% (95% confidence interval, 95%CI 14.7; 20.6), with no significant difference between public and private hospitals. The case fatality ratio was higher in the ≥60 years age group (prevalence ratio, PR 1.26; 95%CI 1.01; 1.58), in hypertensive patients (PR 1.41; 95%CI 1.14; 1 .74) and in those undergoing intensive care (PR 2.68; 95%CI 1.13; 6.32) and mechanical ventilation (PR 11.15; 95%CI 5.53; 22.46). The median time between hospital admission and death was 10 days (interquartile range, 6-18). Survival was lower in the ≥60 years age group (adjusted hazard ratio, HR 1.93; 95%CI 1.26; 2.95) and in those undergoing mechanical ventilation (HR 10.13; 95%CI 6.03; 17. 02).

conclusionFactors related to comorbidities and severity were independent predictors of shorter in-hospital survival among patients with COVID-19.

Indexed as

COVID-19HospitalizationHospital MortalityAdolescentAdultAgedAged, 80 and overBrazilCohort StudiesComorbidityFemaleHospitals, PrivateHospitals, PublicHumansKaplan-Meier EstimateMale

Identifiers

PMID40435037
PMCPMC12105840

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.