Evidence map›Paper›PMID 40435324›Full record

ReviewChemical reviews2025

Molecular Gold Nanoclusters for Advanced NIR-II Bioimaging and Therapy.

Ani Baghdasaryan, Hongjie Dai

Abstract readReview
In one paragraph

Review in Chemical reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Near-Unity Photothermal Conversion in Bimetallic MAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Article
  5. Bandgap-Engineered PtAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Organosilicon cluster goes ferroelectric.National science review · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Gold Quantum Rods Emit in the Shortwave Infrared (1000-2200 nm) with 10Journal of the American Chemical Society · 2026
    Article
  17. Review
  18. Atomically Precise Clusterzymes: A Programmable Optoelectronic Platform for Neuroscience.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ani BaghdasaryanDepartment of Chemistry and Bio-X, Stanford University, Stanford, California 94305, United States.
Hongjie DaiDepartment of Chemistry and Bio-X, Stanford University, Stanford, California 94305, United States.ORCID 0000-0002-4906-4502

Funding

Human Infrared Vision at Molecular and Cellular ScaleDP1NS105737 · NINDS · STANFORD UNIVERSITY · PI DAI, HONGJIE · 2017 to 2022
$5.5M
NINDS NIH HHS DP1 NS105737
6 · The paper itself

Abstract

Small thiolate-protected gold molecular clusters have gained significant interest in research due to their unique size-dependent properties. Their molecular to nanoscale sizes lead to distinctive quantum confinement effects, resulting in a discrete electronic energy band gap structure and molecule-like properties, including HOMO-LUMO electronic transitions, enhanced photoluminescence, and intrinsic magnetism and chirality. Near-infrared II (NIR-II, 1000-3000 nm) emissive gold clusters have emerged as a fascinating class of nanomaterials that are well-suited for biomedical applications. The unique combination of stability, biocompatibility, and tunable emission properties position them as valuable tools for high-resolution and deep-tissue imaging, with potential real-world applications ranging from disease diagnostics and prognosis to therapeutics. In this review, we focus on the NIR-II photoluminescence properties of gold molecular clusters for preclinical in vivo NIR-II imaging of vasculature, brain, kidney, liver, and gastrointestinal organs, and molecular targeted tumor imaging and theranostic treatment. The imaging capabilities combined with fast excretion and a high safety profile make molecular gold clusters highly promising for clinical translation.

Indexed as

GoldMetal NanoparticlesOptical ImagingAnimalsHumansInfrared RaysNeoplasmsTheranostic NanomedicineGold

Identifiers

PMID40435324
PMCPMC12164276

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.