Evidence mapPaperPMID 40435892Full record

ArticleSleep medicine2025

Trajectory of sleep patterns across adolescence in autistic and neurotypical youth.

Beth A Malow, Rachael A Muscatello, Trey McGonigle, Simon Vandekar, Blythe A Corbett

Abstract read
In one paragraph

Article in Sleep medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Beth A MalowVanderbilt University Medical Center, Department of Neurology, Nashville, TN, United States; Vanderbilt University Medical Center, Department of Pediatrics, Nashville, TN, United States; Vanderbilt University Medical Center, Vanderbilt Kennedy Center, Nashville, TN, United States. Electronic address: beth.malow@vumc.org.
Rachael A MuscatelloVanderbilt University Medical Center, Vanderbilt Kennedy Center, Nashville, TN, United States; Vanderbilt University Medical Center, Psychiatry and Behavioral Sciences, Nashville, TN, United States. Electronic address: rachael.a.muscatello.1@vumc.org.
Trey McGonigleVanderbilt University Medical Center, Department of Biostatistics, Nashville, TN, United States. Electronic address: trey.w.mcgonigle@vumc.org.
Simon VandekarVanderbilt University Medical Center, Department of Biostatistics, Nashville, TN, United States. Electronic address: simon.vandekar@vumc.org.
Blythe A CorbettVanderbilt University Medical Center, Vanderbilt Kennedy Center, Nashville, TN, United States; Vanderbilt University Medical Center, Psychiatry and Behavioral Sciences, Nashville, TN, United States; Vanderbilt University, Department of Psychology, Nashville, TN, United States. Electronic address: blythe.corbett@vumc.org.

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · VANDERBILT UNIVERSITY MEDICAL CENTER · 2025 to 2025
$1.2M
Examining Stress and Arousal Across Pubertal Development in ASDR01MH111599 · VANDERBILT UNIVERSITY MEDICAL CENTER · 2025 to 2025
$702k
NCATS NIH HHS UL1 TR000445NICHD NIH HHS P50 HD103537NICHD NIH HHS U54 HD083211NIMH NIH HHS R01 MH111599
6 · The paper itself

Abstract

STUDY

objectivesChanges in sleep-wake patterns are synonymous with the developmental transition to adolescence. To examine the trajectory of sleep-wake patterns in adolescents with autism spectrum disorder (ASD) compared to typically developing (TD) adolescents.

methodsThe total sample consisted of 244 participants, 140 with ASD and 104 who were TD. Sleep data were collected annually in a 4-year longitudinal study on pubertal development, at four time points (10-13 years, 11-14 years, 12-15 years, and 13-16 years). Changes in self-reported weekday and weekend bedtime and waketime across pubertal status were compared between TD and ASD participants, using mixed effects models adjusted for sex, reported night wakings, melatonin use and a diagnosis by puberty interaction. A repeated measures adjusted proportional odds model was used to model reported daytime sleepiness using the same independent variables.

resultsThe ASD and TD groups differed in the change in bedtime across pubertal stages (diagnosis by puberty interaction, X

conclusionsAutistic and TD adolescents exhibit differences in bedtime and daytime sleepiness with pubertal development. These differences may be related to hormonal differences or behavioral factors in these populations and warrant further study.

Indexed as

Autism Spectrum DisorderSleepAdolescentChildFemaleHumansLongitudinal StudiesMalePubertySelf ReportAdolescenceAutismBedtimeDaytime sleepinessPuberty

Identifiers

PMID40435892
PMCPMC12501987

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.