Evidence map›Paper›PMID 40436611›Full record

SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2025

Lung volumes, gas transfer and oscillometry after preterm birth: systematic review and meta-analysis.

James T D Gibbons, Michael L Beaven, Christopher W Course, Sarah J Kotecha, Thomas Hixson, Melissa Zuidersma, Andrew C Wilson, Sailesh Kotecha, Shannon J Simpson

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Physiological responses to exercise in survivors of preterm birth: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Article
  3. Article
  4. Bronchopulmonary dysplasia and extremely preterm birth: time for a broader perspective on long-term outcomes.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

James T D GibbonsChildren's Lung Health, Wal-yan Respiratory Research Centre, The Kids Research Institute of Australia, Perth, Australia.ORCID https://orcid.org/0000-0003-4384-0205
Michael L BeavenChildren's Lung Health, Wal-yan Respiratory Research Centre, The Kids Research Institute of Australia, Perth, Australia.ORCID https://orcid.org/0000-0002-0436-6072
Christopher W CourseDepartment of Child Health, Cardiff University School of Medicine, Cardiff, UK.ORCID https://orcid.org/0000-0002-7789-2057
Sarah J KotechaDepartment of Child Health, Cardiff University School of Medicine, Cardiff, UK.
Thomas HixsonRegional Neonatal Intensive Care Unit, University Hospital of Wales, Cardiff, UK.
Melissa ZuidersmaDepartment of Respiratory and Sleep Medicine, Perth Children's Hospital, Perth, Australia.
Andrew C WilsonChildren's Lung Health, Wal-yan Respiratory Research Centre, The Kids Research Institute of Australia, Perth, Australia.
Sailesh KotechaDepartment of Child Health, Cardiff University School of Medicine, Cardiff, UK.ORCID https://orcid.org/0000-0003-3535-7627
Shannon J SimpsonChildren's Lung Health, Wal-yan Respiratory Research Centre, The Kids Research Institute of Australia, Perth, Australia shannon.simpson@thekids.org.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSmall airway and lung parenchymal abnormalities frequently occur following preterm birth but are commonly missed by spirometry. Static lung volumes, diffusing capacity of the lung for carbon monoxide (

methodsThis systematic review and meta-analysis, registered with PROSPERO (CRD42022320775) and guided by Preferred Reporting Items for Systematic Reviews and Meta-Analyses standards, searched six databases up to 29 December 2024. We included studies comparing lung function between preterm subjects and term controls

resultsFrom 12 143 titles, we analysed 52 cohorts with static lung volumes, 37 with gas transfer and 18 with oscillometry data. While total lung capacity was similar between preterm and term cohorts (SMD -0.08, 95% CI -0.17 to 0.004), preterm participants showed increased residual volume (SMD 0.32, 95% CI 0.19 to 0.44) and residual volume/total lung capacity (SMD 0.45, 95% CI 0.28 to 0.63).

interpretationWe demonstrate that preterm birth is linked to notable abnormalities in static lung volumes, gas transfer and oscillometry, underscoring the necessity of employing comprehensive pulmonary function tests beyond spirometry to monitor and address long-term respiratory outcomes effectively.

Indexed as

LungOscillometryPremature BirthPulmonary Gas ExchangeHumansInfant, NewbornInfant, PrematureLung Volume MeasurementsPulmonary Diffusing Capacity

Identifiers

PMID40436611
PMCPMC12117382

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.