ArticleNature communications2025
Repeated loss of function at HD mating-type genes and of recombination in anther-smut fungi.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed.
- Comparative Analysis of Lifecycle-Dependent A to I RNA Editing in Three Members of theJournal of fungi (Basel, Switzerland) · 2026Article
- Host skin lipids triggerbioRxiv : the preprint server for biology · 2026Article
- Silene, a versatile model system: from sex and genome evolution to ecology and speciation.The New phytologist · 2026Review
- Stepwise recombination suppression around the mating-type locus associated with a diploid-like life cycle in Schizothecium fungi.Molecular biology and evolution · 2026Article
- Chromosome-scale genome assembly ofFrontiers in microbiology · 2026Article
- The complex evolution and genomic dynamics of mating-type loci in Cryptococcus and Kwoniella.PLoS biology · 2025Article
- EASYstrata: an all-in-one workflow for genome annotation and genomic divergence analysis.NAR genomics and bioinformatics · 2025Article
- Tracing the evolution and genomic dynamics of mating-type loci inbioRxiv : the preprint server for biology · 2025Article
- Repeated loss of function at HD mating-type genes and of recombination in anther-smut fungi.Nature communications · 2025Article
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Abstract
Basidiomycete fungi typically have two mating-type loci controlling mating compatibility, HD and PR, residing on different chromosomes. Loss-of-function in mating compatibility has been reported at the PR genes in a few heterothallic basidiomycetes, but not for the HD genes. In Microbotryum anther-smut fungi, there have been repeated linkage events between the HD and PR loci through chromosome fusions, leading to non-recombining regions. Here, we found that two sister Microbotryum species parasitizing Dianthus plants, M. superbum and M. shykoffianum, as well as the distantly related M. scorzonerae, have their HD and PR loci on different chromosomes, but with the PR chromosome fused with a part of the ancestral HD chromosome. In addition, recombination suppression has extended stepwise, generating evolutionary strata. In all three species, the HD genes lost their function in mating compatibility, natural diploid strains being often homozygous at the HD locus. Strains could be homozygous for a disrupted HD2 gene, that was hardly expressed during mating. Mating tests confirmed that a single genetic factor controlled mating compatibility and that haploid strains with identical HD alleles could mate and produce hyphae. This study shows that a unifactorial mating-type determinism can evolve, repeatedly, from a bifactorial system, by different mechanisms.
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