ArticleScientific reports2025
Prompt gamma-ray imaging in realistic background conditions of a boron neutron capture therapy facility.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Quantification ofMedicinal research reviews · 2026Review
- Investigation of a Novel Snout-Mounted Quad-Compton Camera system for In Vivo Proton Dose Verification via Prompt Gamma Imaging.IEEE transactions on radiation and plasma medical sciences · 2026Article
- Nuclear quantum dynamics of boric acid as probed by a thermal-to-epithermal neutron station.Scientific reports · 2025Article
- Evaluation of a CdTe semiconductor-based gamma camera for real-time dose dosimetry in boron neutron capture therapy.Medical physics · 2025Article
- Optimization of the microstructural, mechanical, and radiation shielding properties of Al-30BScientific reports · 2025Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
Boron neutron capture therapy (BNCT) is a highly targeted radiation therapy that shows great promise for treating tumors that are challenging to address with conventional methods. The dose deposited in the tumor during a treatment can be monitored by detecting prompt gamma rays at 478 keV generated by boron neutron capture reactions within the tumor cells. However, this task is highly challenging due to the significant background of neutrons and gamma rays present during treatment that risk to mask the useful signal. An additional challenge is represented by borated polyethylene typically used for radioprotection purposes in the walls of the treatment rooms, which generates gamma rays of the same energy of the ones of clinical interest. To address these issues, we propose a scintillator-based detection system, integrating a pinhole collimator, an artificial neural network for gamma-ray position reconstruction and a multi-layer shielding strategy. This system successfully imaged borated samples with concentrations as low as 1843 ppm of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.