Evidence map›Paper›PMID 40437073›Full record

ArticleThe EMBO journal2025

Structural insights into lipid membrane binding by human ferlins.

Constantin Cretu, Aleksandar Chernev, Csaba Zoltán Kibédi Szabó, Vladimir Pena, Henning Urlaub, Tobias Moser, Julia Preobraschenski

Abstract read
In one paragraph

Article in The EMBO journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Constantin CretuInstitute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany. constantin.cretu@med.uni-goettingen.de.ORCID http://orcid.org/0000-0002-6466-176X
Aleksandar ChernevBioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Csaba Zoltán Kibédi SzabóResearch Group Mechanisms and Regulation of Splicing, The Institute of Cancer Research, London, UK.
Vladimir PenaResearch Group Mechanisms and Regulation of Splicing, The Institute of Cancer Research, London, UK.
Henning UrlaubCluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, Göttingen, Germany.
Tobias MoserInstitute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany. tmoser@gwdg.de.ORCID http://orcid.org/0000-0001-7145-0533
Julia PreobraschenskiInstitute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, Göttingen, Germany. julia.preobraschenski@med.uni-goettingen.de.ORCID http://orcid.org/0000-0002-1825-0433

Funding

Deutsche Forschungsgemeinschaft (DFG) 448415290Deutsche Forschungsgemeinschaft (DFG) CR 937/2-1Deutsche Forschungsgemeinschaft (DFG) EXC 2067/1-390729940Deutsche Forschungsgemeinschaft (DFG) MO896/5Deutsche Forschungsgemeinschaft (DFG) SFB889,Project A11Fondation Pour l'Audition (FPA) FPA RD-2020-10Wellcome Trust 220300Wellcome Trust (WT) 220300Z/20/Z
6 · The paper itself

Abstract

Ferlins are ancient membrane proteins with a unique architecture, and play central roles in crucial processes that involve Ca

Indexed as

Calcium-Binding ProteinsDysferlinLipid BilayersMembrane LipidsMembrane ProteinsMuscle ProteinsCalciumCryoelectron MicroscopyHumansModels, MolecularProtein BindingProtein ConformationCalciumCalcium-Binding ProteinsDysferlinDYSF protein, humanLipid BilayersMembrane LipidsMembrane ProteinsMuscle ProteinsMYOF protein, humanC2 DomainCa2+ Sensing and SignallingCryo-EMFerlinsMembrane Fusion

Identifiers

PMID40437073
PMCPMC12264198

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.