Evidence map›Paper›PMID 40437291›Full record

ArticleObesity surgery2025

Bariatric Surgery and Lung Transplant Outcomes: Case Series and Insights from a Propensity-Matched Analysis at a High-Volume Transplant Center.

Andrés Latorre-Rodriguez, Mark Shacker, Hesham Mohamed, Ross M Bremner, Sumeet K Mittal

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Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Andrés Latorre-RodriguezSt. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.
Mark ShackerCreighton University, Phoenix, AZ, USA.
Hesham MohamedSt. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.
Ross M BremnerSt. Joseph's Hospital and Medical Center, Phoenix, AZ, USA.
Sumeet K MittalSt. Joseph's Hospital and Medical Center, Phoenix, AZ, USA. sumeet.mittal@commonspirit.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAn increasing number of patients with a history of bariatric surgery and advanced respiratory disease are presenting for lung transplantation (LTx). We aimed to describe and compare LTx outcomes between recipients with prior bariatric surgery and a matched control group at a high-volume lung transplant center.

methodsAfter IRB approval, we identified bilateral LTx recipients with a pre-LTx history of bariatric surgery (Roux-en-Y gastric bypass [RYGB], sleeve gastrectomy [SG], or laparoscopic adjustable gastric band [LAGB]). The institutional experience is reported as a case series. Furthermore, perioperative and mid-term transplant outcomes such primary graft dysfunction (PGD), antibody-mediated rejection (AMR), acute cellular rejection (ACR), chronic lung allograft dysfunction (CLAD)-free survival, and overall survival (OS) were compared to a 1-to-2 propensity score-matched control group.

resultsNine patients (median age: 65 years; 77.8% female) with a history of bariatric surgery (RYGB = 4, SG = 4, LAGB = 1) a median of 76 months before LTx were included. The median hospital length of stay (LOS) and ICU-LOS were similar to the control group (n = 18). Moreover, 1-, 2-, and 3-year OS in bariatric and control groups were similar (88.9%, 88.9%, and 66.7% vs. 100%, 86.7%, and 78%, respectively; p = 0.27). CLAD-free survival and rates of PGD, AMR, and ACR were also similar.

conclusionsPrior bariatric surgery may not affect overall or CLAD-free survival after bilateral LTx. Bariatric surgery for obesity treatment in patients with advanced lung diseases may improve their LTx candidacy without compromising early and mid-term transplant outcomes.

Indexed as

Bariatric SurgeryLung TransplantationObesity, MorbidAgedFemaleGraft RejectionHospitals, High-VolumeHumansLength of StayMaleMiddle AgedPrimary Graft DysfunctionPropensity ScoreRetrospective StudiesTreatment OutcomeBariatric surgeryChronic lung allograft dysfunctionGastroesophageal refluxLung transplantationMetabolic surgeryObesity

Identifiers

PMID40437291
PMCPMC12271277

What Socratic holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.