Evidence map›Paper›PMID 40437352›Full record

ArticleBMC plant biology2025

Transcriptomic analysis of Phytophthora infestans races and evaluation of their pathogenicity on potato.

Linmei Deng, Jianjun Hao, Jiawen Feng, Jing Zhao, Jian Dao, Gaihuan Xu, Kunyan Zhou, Yajin Xu, Wenping Wang, Shunhong Zhang and 4 more

Abstract read
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Phosphite inhibitsFrontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Linmei DengKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Jianjun HaoSchool of Food and Agriculture, The University of Maine, Orono, 04469, ME, U.S.A.
Jiawen FengAgricultural and Rural Bureau, Qujing, 655199, China.
Jing ZhaoKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Jian DaoKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Gaihuan XuKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Kunyan ZhouKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Yajin XuKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Wenping WangKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Shunhong ZhangKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Chunjiang LiuKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Meng ChenKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China.
Yanli YangKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China. yangyanliyyl@foxmail.com.
Xia LiuKey Laboratory for Agro-biodiversity and Pest Control of Ministry of Education, College of Plant Protection, Yunnan Agricultural University, Kunming, 650201, China. liuxia_0213@163.com.

Funding

the Major Science and Technology Projects in Yunnan Province 202402AE090017the Modern Agricultural Potato Industry Technology System in Yunnan Province 2024KJTX-04the National Key Research and Development Program of China 2024YFD1401200
6 · The paper itself

Abstract

Phytophthora infestans causes potato late blight and significantly impacts potato production. The pathogen's remarkable adaptability and ability to generate new physiological races through virulence variation undermine varietal resistance, posing challenges for disease prevention and control. To explore the genetic mechanisms behind these, different physiological races of P. infestans were inoculated on potato leaves and assayed through transcriptomics combined with metabolic profiling methods. It was found that the DL04 strain, which carries virulence factor 3, exhibited a high level of pathogenicity. Biologically, DL04 showed more rapid growth and denser mycelial structures compared to most other strains, indicating enhanced pathogenicity. DL04 induced a greater enrichment of carbon metabolism, biosynthesis of amino acids, and glycolysis/gluconeogenesis pathways during the infection process. This led to the upregulation of genes related to cell hydrolysis, accelerating leaf infection and contributing to its higher level of pathogenicity. The reasons for the differences in pathogenicity among different physiological races of P. infestans were clarified at the transcriptional level. This finding provides valuable insights into the genetic basis of P. infestans pathogenicity and offer critical information for developing effective control strategies, breeding for disease resistance, and improving potato production practice.

Indexed as

Phytophthora infestansPlant DiseasesSolanum tuberosumTranscriptomeGene Expression ProfilingPlant LeavesVirulenceGenetic analysisLate blightMetabolic pathwaysPhysiological racesPotato resistance

Identifiers

PMID40437352
PMCPMC12117779

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.