ArticleRenal failure2025
Application value of weight-adjusted waist circumference index and cardiometabolic index in hypertensive patients with albuminuria: results from the National Health and Nutrition Examination Survey 2005-2020.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Weight-adjusted Waist Index (WWI) and Cardiometabolic Index (CMI) are novel metrics developed to evaluate visceral fat distribution and metabolic health. This study aimed to explore the associations between these indices and albuminuria in hypertensive patients.
methodsWe conducted a cross-sectional analysis using data from the National Health and Nutrition Examination Survey (NHANES), obtained between 2005 and 2020. Multivariate logistic regression models, generalized additive models, and smooth curve fitting were employed to examine the relationships between WWI, CMI, and albuminuria. Nonlinear associations were further investigated using a piecewise linear model to identify inflection points. Subgroup analyses were performed, and the diagnostic performance of these indices was evaluated using Receiver Operating Characteristic (ROC) curves.
resultsAfter adjusting for potential confounders, both WWI and CMI were significantly associated with increased odds of albuminuria (OR = 1.37 and 1.09, respectively). The relationship between WWI and urinary albumin-creatinine ratio (UACR) exhibited a nonlinear pattern, with an inflection point at 11.65. For WWI values lower than 11.65, significant correlations were observed. Subgroup analysis revealed a stronger association between WWI and albuminuria in males. ROC curve analysis indicated that WWI outperformed CMI in detecting albuminuria, with CMI showing slightly lower diagnostic accuracy. When combined with other clinical indicators, the integrated area under the curve (AUC) reached 0.732.
conclusionBoth WWI and CMI demonstrated significant associations with albuminuria in hypertensive patients, highlighting their potential utility in disease screening. Clinical attention should be directed toward individuals with WWI below 11.65, particularly male subjects, as this threshold was associated with significantly increased prevalence of albuminuria.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.