Evidence map›Paper›PMID 40437898›Full record

SynthesisBrain and behavior2025

The Relationship Between Body Mass Index and Recurrence Risk of Stroke: A Systematic Review and Dose-Response Meta‑Analysis.

Qiuxia Qian, Yuting Zhao, Xin Fan, Jialu Li, Jianxun Cao, Mengyu Yang, Longchun Hua, Xingxia Zhang, Ailing Yang, Fengwa Zhang and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qiuxia QianEvidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0009-0004-8710-1820
Yuting ZhaoEvidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, China.
Xin FanEvidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, China.
Jialu LiEvidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, China.
Jianxun CaoDepartment of Radiology, Gansu Provincial Hospital, Lanzhou, Gansu, China.
Mengyu YangEvidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, China.
Longchun HuaDepartment of Digestive Endoscopy, Gansu Provincial Hospital, Lanzhou, Gansu, China.
Xingxia ZhangOperating Room, Gansu Third People's Hospital, Lanzhou, Gansu, China.
Ailing YangThe Second Hospital, Lanzhou University, Lanzhou, Gansu, China.
Fengwa ZhangBurns Surgery/Plastic Surgery, Gansu Provincial Hospital, Lanzhou, Gansu, China.
Yuxia MaEvidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, China.

Funding

Key Research and Development Program of Gansu Province 23YFFA0006National Natural Science Foundation of China 72474092Nature Science Foundation of Gansu Province 25JRRA300Scientific research project of health industry in Gansu Province GSWSHL2020-17Scientific research project of health industry in Gansu Province GSWSHL2022-34
6 · The paper itself

Abstract

objectiveTo explore the relationship between body mass index (BMI) and the recurrence risk of stroke.

methodsWe searched databases, including the Web of Science, Cochrane Library, Embase, PubMed, Chinese Biomedical Literature (CBM), CQVIP, WanFang Database, and China National Knowledge Infrastructure (CNKI), from inception to February 2025, to collect literature on BMI and the recurrence risk of stroke. After two researchers independently screened the literature, extracted the literature data, and assessed the quality of the literature included in the study, a meta-analysis was conducted using Stata 16.0 software, and the dose-response relationship between BMI and the recurrence risk of stroke was analyzed using generalized least squares trend estimation method (GLST) and restricted cubic spline function.

resultsA total of 18 studies were included, involving 165,366 patients. In terms of stroke recurrence risk, compared with normal-weight patients, underweight patients [relative risk (RR) = 1.59, 95% confidence interval (CI) 1.33-1.90, I

conclusionIncreased BMI is associated with a decreased recurrence risk of stroke. Underweight is a risk factor for stroke recurrence, whereas overweight and obesity are protective factors for stroke recurrence. Overweight and obesity may be beneficial for secondary prevention in stroke patients. CLINICAL

trial registrationNot applicable.

Indexed as

Body Mass IndexStrokeHumansObesityOverweightRecurrenceRisk FactorsThinnessbody mass indexdose–response analysismeta‐analysisstroke recurrence

Identifiers

PMID40437898
PMCPMC12120265

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.