Evidence map›Paper›PMID 40438343›Full record

ArticleFrontiers in nutrition2025

Unveiling the therapeutic benefits of black chokeberry (

Chin-Yuan Liu, Wen-Yu Liu, Yeu-Ching Shi, She-Ching Wu

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Black Chokeberry Extracts (Molecules (Basel, Switzerland) · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chin-Yuan Liu *Department of Food Sciences, National Chiayi University, Chiayi, Taiwan.
Wen-Yu Liu *Department of Food Safety/Hygiene and Risk Management, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yeu-Ching ShiDepartment of Food Sciences, National Chiayi University, Chiayi, Taiwan.
She-Ching WuDepartment of Food Sciences, National Chiayi University, Chiayi, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hyperuricemia not only increases the risk of cardiovascular diseases such as dyslipidemia, hypertension, coronary artery disease, obesity, metabolic syndrome, and type-2 diabetes, but also severely impacts kidney function, potentially leading to acute kidney injury and chronic kidney disease. Methods: This study aims to investigate the health benefits of black chokeberry ( Result: The experimental results showed that black chokeberry had no significant toxic or negative effects in mice. The measurement of uric acid (UA) indicated that black chokeberry suppressed the UA levels. Additionally, the xanthine oxidase activity in the high-dose group was significantly decreased, along with reductions in serum urea nitrogen and creatinine levels. Black chokeberry effectively increased the glutathione levels in hyperuricemic mice and reduced malondialdehyde levels, as well as significantly inhibiting adenosine deaminase activity. Conclusion: Its efficacy is comparable to that of the marketed drug allopurinol, underscoring the potential of black chokeberry as a functional product for uric acid reduction.

Indexed as

adenosine deaminaseblack chokeberryhyperuricemiauric acidxanthine oxidase

Identifiers

PMID40438343
PMCPMC12118122

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.