Evidence map›Paper›PMID 40438940›Full record

ArticleRNA biology2025

RNA-seq analyses reveal the relevance of RNAs involved in ribosomal complex to induce mammalian prion protein aggregation and phase separation

Ana C Tahira, Mariana P B Gomes, Maria Heloisa Freire, Marcelly Muxfeldt, Francisco Prosdocimi, Yulli M Passos, Murilo Sena Amaral, Leticia P Felix Valadão, Luciana P Rangel, Jerson L Silva and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ana C TahiraLaboratório de Ciclo Celular, Instituto Butantan, São Paulo, Brasil.
Mariana P B GomesFaculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Maria Heloisa FreireFaculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Marcelly MuxfeldtFaculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Francisco ProsdocimiInstituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Yulli M PassosFaculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Murilo Sena AmaralLaboratório de Ciclo Celular, Instituto Butantan, São Paulo, Brasil.
Leticia P Felix ValadãoFaculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Luciana P RangelFaculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Jerson L SilvaInstituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Sergio Verjovski-AlmeidaLaboratório de Ciclo Celular, Instituto Butantan, São Paulo, Brasil.
Yraima CordeiroFaculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.ORCID 0000-0003-4278-212X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conformational conversion of cellular prion protein (PrP

Indexed as

Prion ProteinsRibosomesRNARNA, RibosomalAnimalsCell Line, TumorMicePhase SeparationProtein AggregatesRNA-SeqPrion ProteinsProtein AggregatesRNARNA, RibosomalChIP-seqliquid-liquid phase separationneurodegenerative diseasesnucleic acidprion diseasesPrion proteinprotein aggregationprotein-nucleic acid interactionRNARNA-seq

Identifiers

PMID40438940
PMCPMC12123958

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.