Evidence map›Paper›PMID 40438985›Full record

ArticleHaematologica2025

Chronic lymphocytic leukemia and associated chronic lung diseases.

Tamar Tadmor, Emilia Hardak, Guy Melamed, Hilel Alapi, Lior Rokach

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Haematologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tamar TadmorHematology Unit, Bnai Zion Medical Center, and the Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa. tamar.tadmor@b-zion.org.il.
Emilia HardakPulmonary Unit, Bnai Zion Medical Center, Faculty of Medicine, Technion, Haifa.
Guy MelamedKahn Sagol Maccabi Research and Innovation Center, Maccabi Healthcare Services, Tel-Aviv.
Hilel AlapiKahn Sagol Maccabi Research and Innovation Center, Maccabi Healthcare Services, Tel-Aviv.
Lior RokachDepartment of Software and Information Systems Engineering, Ben-Gurion University of the Negev, Beer-Sheva.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections are a significant cause of morbidity and mortality in chronic lymphocytic leukemia (CLL), with respiratory tract infections being predominant. This study evaluated the incidence of chronic lung diseases (asthma, chronic obstructive pulmonary disease [COPD], and bronchiectasis) among 4,532 patients with CLL and their association with infection complications and outcomes. We found that bronchiectasis (5%), asthma (12.2%), and COPD (6.6%) were prevalent among CLL patients and were associated with an increased hazard ratio (HR) for pneumonia (HR=1.7). Bronchiectasis and COPD were significantly associated with higher rates of hospitalization due to pneumonia. Preventive measures, such as Prevenar vaccination and intravenous immunoglobulin therapy, reduced pneumonia-related hospitalizations. These findings underscore the importance of early diagnosis and management of chronic lung diseases in CLL patients.

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellLung DiseasesAdultAgedAged, 80 and overChronic DiseaseFemaleHumansIncidenceMaleMiddle AgedPulmonary Disease, Chronic Obstructive

Identifiers

PMID40438985
PMCPMC12580690

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.