Evidence mapPaperPMID 40439155Full record

Observational studyJournal of the American Heart Association2025

Heterogeneous Exercise Responses to High-Intensity Interval Training Are Associated With Varied Long-Term Cardiovascular Outcomes in Patients With Heart Failure: A 15-Year Follow-Up.

Tieh-Cheng Fu, Shu-Chun Huang, Shin-Sheng Yuan, Chao-Hung Wang, Jong-Shyan Wang, Wen-Chung Tsai, Wen-Jin Cherng, Yu-Chiau Shyu, Chih-Chin Hsu

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Tieh-Cheng FuDepartment of Physical Medicine and Rehabilitation Keelung Chang Gung Memorial Hospital Keelung Taiwan.ORCID 0000-0002-8702-0391
Shu-Chun HuangSchool of Medicine, College of Medicine Chang Gung University Taoyuan Taiwan.ORCID 0000-0001-6816-8836
Shin-Sheng YuanInstitute of Statistical Science, Academia Sinica Taipei Taiwan.
Chao-Hung WangSchool of Medicine, College of Medicine Chang Gung University Taoyuan Taiwan.ORCID 0000-0001-5468-4354
Jong-Shyan WangDepartment of Physical Medicine and Rehabilitation Keelung Chang Gung Memorial Hospital Keelung Taiwan.ORCID 0000-0002-3095-9357
Wen-Chung TsaiSchool of Medicine, College of Medicine Chang Gung University Taoyuan Taiwan.
Wen-Jin CherngDivision of Cardiology, Department of Internal Medicine Linkou Chang Gung Memorial Hospital Taoyuan Taiwan.ORCID 0000-0003-4670-4460
Yu-Chiau ShyuCommunity Medicine Research Center, Keelung Chang Gung Memorial Hospital Keelung Taiwan.ORCID 0000-0003-1747-2226
Chih-Chin HsuDepartment of Physical Medicine and Rehabilitation Keelung Chang Gung Memorial Hospital Keelung Taiwan.ORCID 0000-0002-5558-3456

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study investigated exercise response heterogeneity and its mediating role in survival for patients with heart failure. METHODS AND

resultsWe conducted a retrospective cohort study by examining the registry satabase in 3 institutes from 2009 to 2024. All 182 included patients with heart failure completed 36 sessions of high-intensity interval training (HIIT) at alternating intensities of 80% and 40% peak oxygen consumption (

conclusionsThe longitudinal study has identified different physiological adaptations to HIIT in patients with heart failure. Improvement of cardiorespiratory fitness appears to be the dominant factor in reduction of the cardiovascular event for patients with heart failure.

Indexed as

Exercise ToleranceHeart FailureHigh-Intensity Interval TrainingAgedCardiorespiratory FitnessFemaleFollow-Up StudiesHumansMaleMiddle AgedOxygen ConsumptionPatient ReadmissionRegistriesRetrospective StudiesTime FactorsTreatment Outcomeevent‐free survivalexercise response heterogeneityheart failurehigh‐intensity interval trainingmediation

Identifiers

PMID40439155
PMCPMC12229121

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.