Evidence map›Paper›PMID 40439451›Full record

Observational studyEmerging infectious diseases2025

Long-Term Clinical Outcomes of Adults Hospitalized for COVID-19 Pneumonia.

Ivan O Rosas, Alejandra Benitez, James A McKinnell, Reena Shah, Michael Waters, Bradley D Hunter, Robert Jeanfreau, Larry Tsai, Margaret Neighbors, Ben Trzaskoma and 2 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Emerging infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ivan O Rosas
Alejandra Benitez
James A McKinnell
Reena Shah
Michael Waters
Bradley D Hunter
Robert Jeanfreau
Larry Tsai
Margaret Neighbors
Ben Trzaskoma
Rita de Cassia Castro
Fang Cai

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a multicenter, observational, 12-month follow-up study to identify the extended health burden of severe COVID-19 pneumonia by characterizing long-term sequelae of acute infection in participants previously enrolled in clinical trials for severe COVID-19 pneumonia requiring hospitalization. Overall, 134 (77.5%) of 173 participants completed the study. At 12 months, 51 (29.5%) participants reported cough, 60 (34.7%) reported dyspnea, 56 (32.4%) had residual lung texture abnormalities on high-resolution computed tomography scans, 26 (15.0%) had impaired forced vital capacity, 52 (30.1%) had cognitive impairment, and 77 (44.5%) reported fatigue. Disease severity during acute infection and age were associated with persistent lung texture abnormalities; history of hypertension was associated with higher prevalence of fatigue and more frequent dyspnea and cough; and age and obesity were associated with long-term cognitive impairment. Our findings underscore the long-term health burden of severe COVID-19 pneumonia, reinforcing the importance of regular monitoring in older persons and those with underlying illnesses.

Indexed as

COVID-19HospitalizationAdultAgedAged, 80 and overCognitive DysfunctionFatigueFemaleFollow-Up StudiesHumansLungMaleMiddle AgedSARS-CoV-2Severity of Illness IndexTomography, X-Ray Computedcognitive dysfunctioncoronaviruscoronavirus diseaseCOVID-19heart function testsKenyapatient-reported outcome measuresPerupost-acute COVID-19 syndromepulmonary function testsrespiratory infectionsSARSSARS-CoV-2severe acute respiratory syndrome coronavirus 2United Statesviruseszoonoses

Identifiers

PMID40439451
PMCPMC12123926

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.