Evidence mapPaperPMID 40440475Full record

ArticleJBRA assisted reproduction2025

Does flying after embryo transfer impact implantation?

João Antonio Dias, Carlos Roberto Izzo, Georges Fassolas, Luiz Fernando Henrique, Denis Schapira Wajman

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Article in JBRA assisted reproduction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

João Antonio DiasClínica Originare Medicina Reprodutiva, São Paulo, SP, Brazil.
Carlos Roberto IzzoClínica Originare Medicina Reprodutiva, São Paulo, SP, Brazil.
Georges FassolasClínica Originare Medicina Reprodutiva, São Paulo, SP, Brazil.
Luiz Fernando HenriqueClínica Originare Medicina Reprodutiva, São Paulo, SP, Brazil.
Denis Schapira WajmanClínica Originare Medicina Reprodutiva, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore whether post-embryo transfer (ET) air travel affects in vitro fertilization (IVF) outcomes, addressing the growing concern in medical tourism where patients frequently travel for fertility treatments.

methodsThis retrospective study was conducted at a private fertility clinic in São Paulo, Brazil, and included 2,135 embryo transfers performed between January 2019 and March 2022. Patients were divided into two groups: individuals who presumably traveled by airplane after ET (Group 2) and those who did not (Group 1). Data were analyzed for demographics, embryo transfer characteristics, and IVF outcomes. Relative risk was estimated using Poisson regression models, adjusting for age and treatment reasons. Significance was set at p<0.05.

results17.94% of patients traveled by plane post-ET. No significant differences were found between the groups in terms of pregnancy (Group 1: 61.99%, Group 2: 62.14%, p=0.94), implantation (Group 1: 34.58%, Group 2: 38.65%, p=0.28), or miscarriage rates (Group 1: 28.51%, Group 2: 32.50%, p=0.32). A sub-analysis of single embryo transfers and top embryos also showed no statistical differences.

conclusionsPost-ET air travel did not negatively impact IVF treatment outcomes. Further prospective studies are recommended to confirm these findings.

Indexed as

Air TravelEmbryo ImplantationEmbryo TransferFertilization in VitroMedical TourismAdultBrazilFemaleHumansPregnancyPregnancy RateRetrospective Studiesair travelembryo transferimplantationIVF outcomesmedical tourism

Identifiers

PMID40440475
PMCPMC12469480

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