Evidence map›Paper›PMID 40442113›Full record

ArticleNPJ science of food2025

From phytochemicals to recipes: health indications and culinary uses of herbs and spices.

Rishemjit Kaur, Shuchen Zhang, Bhavika Berwal, Sonalika Ray, Ritesh Kumar, Lav R Varshney

Abstract read
In one paragraph

Article in NPJ science of food, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rishemjit KaurCSIR-Central Scientific Instruments Organisation, Chandigarh, India.
Shuchen ZhangUniversity of Illinois Urbana-Champaign, Urbana, IL, USA.
Bhavika BerwalCSIR-Central Scientific Instruments Organisation, Chandigarh, India.
Sonalika RayCSIR-Central Scientific Instruments Organisation, Chandigarh, India.
Ritesh KumarCSIR-Central Scientific Instruments Organisation, Chandigarh, India.
Lav R VarshneyUniversity of Illinois Urbana-Champaign, Urbana, IL, USA. varshney@illinois.edu.

Funding

CSIR ATLAS mission HCP0031
6 · The paper itself

Abstract

Herbs and spices each contain about 3000 phytochemicals on average, and there is much traditional knowledge on their health benefits. However, there is a lack of systematic studies to understand the relationship among herbs and spices, their phytochemical constituents, their potential health benefits, and their usage in regional cuisines. Here, we use a network-based approach to elucidate established relationships and predict novel associations between the phytochemicals present in herbs and spices and health indications. Our top 100 inferred indication-phytochemical relationships rediscover 40% known relationships and 20% that have been inferred via gene-chemical interactions with high confidence. The remaining 40% are hypotheses generated in a principled way for further experimental investigations. We also develop an algorithm to find the minimum set of spices needed to cover a target group of health conditions. Drawing on spice usage patterns in several regional Indian cuisines and a copy-mutate model for regional cuisine evolution, we characterize the spectrum of health conditions covered by existing regional cuisines. The spectrum of health conditions can expand through the nationalization/globalization of culinary practice.

Identifiers

PMID40442113
PMCPMC12122677

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.