ArticleFrontiers in physiology2025
Association of triglyceride-glucose index and its combinations with sarcopenia among community-dwelling older adults: based on the Chongqing Aging and Sarcopenia Evaluation (CHASE) cohort.
Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
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Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Associations between the triglyceride‒glucose index and the odds of low muscle mass and sarcopenia: a systematic review and meta-analysis.BMC endocrine disorders · 2026Pooled it
- Pooled it
- Insulin resistance-related indices, sarcopenia, and cardiovascular risk in CKM stages 1-3: a prospective cohort study from CHARLS.BMC endocrine disorders · 2026Article
- A w-ACT model for sarcopenia among community-dwelling older adults based on National Basic Public Health Services: development and validation study.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
9 authors.
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Abstract
Background: The triglyceride-glucose (TyG) index serves as an alternative index for assessing insulin resistance (IR). The relationship between the TyG index and its combined indicators and sarcopenia remains insufficiently explored. Aim: To investigate the association between the TyG index and its combined parameters and sarcopenia. Methods: This cross-sectional study encompassed 792 community-dwelling older adults from the Chongqing Aging and Sarcopenia Evaluation (CHASE) cohort. The multivariate logistic regression model was used to analyze the relationship between the TyG index and its combined parameters, which include the triglyceride glucose-body mass index (TyG-BMI), triglyceride glucose-calf girth (TyG-CG), triglyceride glucose-waist circumference (TyG-WC), and triglyceride glucose-waist-to-hip ratio (TyG-WHR). The receiver operator characteristic (ROC) curve was utilized to assess the diagnostic effect of each index. The integrated discrimination improvement index (IDI) and net reclassification improvement (NRI) were applied to compare the diagnostic efficacy among the indices. Results: The TyG index and its combined parameters demonstrated a significant correlation with the risk of sarcopenia ( Conclusion: The TyG index demonstrates diagnostic potential for sarcopenia identification, with significantly enhanced accuracy when combined with other parameters. Among them, TyG-BMI is a robust sarcopenia risk predictor due to its superior predictive power.
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