Evidence map›Paper›PMID 40443667›Full record

ArticleFrontiers in immunology2025

Bioinformatics analyses of the proteome of

Laura La Paglia, Manuela Mauro, Vincenzo Arizza, Alfonso Urso, Sugár Simon, Laszlo Drahos, Vita di Stefano, Claudio Luparello, Mirella Vazzana, Aiti Vizzini

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Laura La Paglia *Institute of High Performance Computing and Networking (ICAR)-CNR, National Research Council of Italy, Palermo, Italy.
Manuela Mauro *Department of Biological and Technological Science, Chemical and Pharmaceutical Science (STEBICEF), University of Studies of Palermo, Palermo, Italy.
Vincenzo ArizzaDepartment of Biological and Technological Science, Chemical and Pharmaceutical Science (STEBICEF), University of Studies of Palermo, Palermo, Italy.
Alfonso UrsoInstitute of High Performance Computing and Networking (ICAR)-CNR, National Research Council of Italy, Palermo, Italy.
Sugár SimonMass Spectrometry (MS) Proteomics Research Group, Research Centre for Natural Sciences, Budapest, Hungary.
Laszlo DrahosMass Spectrometry (MS) Proteomics Research Group, Research Centre for Natural Sciences, Budapest, Hungary.
Vita di StefanoDepartment of Biological and Technological Science, Chemical and Pharmaceutical Science (STEBICEF), University of Studies of Palermo, Palermo, Italy.
Claudio LuparelloDepartment of Biological and Technological Science, Chemical and Pharmaceutical Science (STEBICEF), University of Studies of Palermo, Palermo, Italy.
Mirella VazzanaDepartment of Biological and Technological Science, Chemical and Pharmaceutical Science (STEBICEF), University of Studies of Palermo, Palermo, Italy.
Aiti VizziniDepartment of Biological and Technological Science, Chemical and Pharmaceutical Science (STEBICEF), University of Studies of Palermo, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The holothurian immune system is characterized by complex defense mechanisms that act through humoral and cellular pathways. Coelomocites are the cellular component of coelomic fluid, and they are involved in host defense, stress response, wound healing, organ regeneration, and tissue homeostasis. The close phylogenetic relationship between

Indexed as

Body FluidsCiliaComputational BiologyHolothuriaProteomeAnimalsHumansPhylogenyProteomicsProteomebioinformaticscoelomic fluidcoelomocytesechinodermHolothuria tubulosainnate immunityprimary ciliumproteomics

Identifiers

PMID40443667
PMCPMC12119288

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.