ArticleFood science & nutrition2025
The Potential Role of Egg-Derived Xeno-miRs in Chemotherapy Response: An In Silico Approach.
Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exogenous microRNAs (Xeno-miRs), primarily derived from dietary sources, are detectable in host biofluids and influence gene expression through cross-kingdom regulation. Despite growing interest, their impact on human diseases, especially cancer, remains controversial and requires further investigation. However, the specific implications of diet-derived Xeno-miRs in chemotherapy response remain largely unexplored. This study assesses the potential functions and possible implications of egg-derived miRNAs in chemotherapy response with an in silico approach. This study presents the first evaluation of the contribution of diet-derived miRNAs in modulating chemotherapy outcomes. Egg-derived miRNAs were retrieved from the Dietary MicroRNA Database, and their human homologs were identified. Target genes and transcription factors were predicted using mirDIP and TransmiR databases, respectively. Pathway enrichment analysis was conducted with DIANA-miRPath. Expression patterns of Xeno-miRs were analyzed using the CancerMIRNome database, and differentially expressed target genes were identified using TCGA and GTEx data via GEPIA2. The chemotherapy response of Xeno-miRs was assessed using ncRNADrug. Fifty-five egg-derived Xeno-miRs were initially retrieved, among which 17 human homologs were further analyzed. Notably, the downregulation of
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.