SynthesisPeerJ2025
Association between gut microbiota and allergic rhinitis: a systematic review and meta-analysis.
Synthesis in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Traditional Chinese Medicine for Allergic Rhinitis: Mechanisms, Evidence, and Gut-Immune Axis Targets.Journal of asthma and allergy · 2026Review
- Exploring putative links between gut microbiota and allergic rhinitis: insights from Mendelian randomization and multi-transcriptome integration.AMB Express · 2025Article
- Integrated gut microbiome and metabolomics analysis reveals microbial-metabolic cross-talk in allergic rhinitis.Frontiers in microbiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Many studies have shown that allergic rhinitis (AR) is closely related to intestinal flora, and probiotics are effective in treatment. However, the results of human observational studies on the correlation between intestinal flora and AR have been contradictory. The aim of this study was to determine the relationship between gut microbiota and allergic rhinitis and to provide a clinical reference. Methods: PubMed, Web of Science, Medline, Embase, Cochrane Library, and Cinahl databases were searched, and the literature on the correlation between allergic rhinitis and the gut microbiota reported from database establishment to December 2023 was included. Literature meeting the inclusion criteria was screened, and meta-analysis of the included literature was performed using R software (4.3.3). Literature quality underwent assessment utilizing the Newcastle-Ottawa Quality Assessment Scale. Hedge's g standardized mean difference (SMD), confidence intervals (CIs), and heterogeneity ( Results: A total of 10 observational studies in humans were conducted, identifying 550 patients with AR and 385 healthy individuals. No statistically significant differences were observed in alpha diversity between two groups, including Shannon index (SMD = -0.3938, 95% CI [-0.9847-0.1972], Conclusions: The currently available evidence does not suggest that patients with allergic rhinitis may have similar intestinal flora imbalances. Nevertheless, further corroboration is required with larger samples and higher-quality studies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.