Evidence map›Paper›PMID 40445333›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2025

Temperature alters the inotropic and chronotropic effect of D

Peter Grundig, Thanh Hoai Pham, Britt Hofmann, Joachim Neumann, Ulrich Gergs

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Initial characterization of MNaunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peter Grundig *Institute for Pharmacology and Toxicology, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Magdeburger Straße 4, 06097, Halle (Saale), Germany.
Thanh Hoai Pham *Institute for Pharmacology and Toxicology, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Magdeburger Straße 4, 06097, Halle (Saale), Germany.
Britt HofmannDepartment of Cardiac Surgery, Mid-German Heart Centre, University Hospital Halle, Ernst-Grube-Str. 40, D‑06097, Halle (Saale), Germany.
Joachim NeumannInstitute for Pharmacology and Toxicology, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Magdeburger Straße 4, 06097, Halle (Saale), Germany. joachim.neumann@medizin.uni-halle.de.
Ulrich GergsInstitute for Pharmacology and Toxicology, Medical Faculty, Martin-Luther-University Halle-Wittenberg, Magdeburger Straße 4, 06097, Halle (Saale), Germany.

Funding

Deutsche Forschungsgemeinschaft 519414516
6 · The paper itself

Abstract

We studied how hypothermia and hyperthermia may change the efficacy and/or potency of dopamine to augment the force of contraction in atria of mice with cardiac overexpression of the human D

Indexed as

DopamineHeart AtriaMyocardial ContractionReceptors, Dopamine D1AnimalsAtrial FunctionFemaleHeart RateHumansMaleMiceMice, Inbred C57BLMice, TransgenicTemperatureDopamineReceptors, Dopamine D1ArrhythmiaChronotropyD1-dopamine receptorDopamineHyperthermiaHypothermiaInotropy

Identifiers

PMID40445333
PMCPMC12552296

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.