Evidence map›Paper›PMID 40450377›Full record

ArticleJournal of health, population, and nutrition2025

Diet-induced inflammation and its association with sarcopenia in an Iranian population: a case-control study.

Neda Heidarzadeh-Esfahani, Sevda Eskandarzadeh, Marzieh Mahmoodi, Maede Makhtoomi, Seyyed Mohammad Alavi, Zainab Shateri, Nasrin Nasimi, Mehran Nouri, Mohammad Hossein Dabbaghmanesh

Abstract read
In one paragraph

Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Neda Heidarzadeh-EsfahaniDepartment of Nutrition, Iranian Cancer Control Center (MACSA) - Isfahan Branch, Isfahan, Iran.ORCID 0000-0002-3740-2930
Sevda EskandarzadehDepartment of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Marzieh MahmoodiDepartment of Nutrition, Faculty of Health and Nutrition, Bushehr University of Medical Sciences, Bushehr, Iran.
Maede MakhtoomiHealth Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
Seyyed Mohammad AlaviDepartment of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0009-0001-8924-1454
Zainab ShateriDepartment of Nutrition and Biochemistry, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.ORCID 0000-0003-3725-6686
Nasrin NasimiDepartment of Community Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Mehran NouriInfertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. mehran_nouri71@yahoo.com.ORCID 0000-0002-7031-3542
Mohammad Hossein DabbaghmaneshEndocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. dabbaghm@sums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDietary intake, as one of the critical lifestyle risk factors, plays a crucial role in the risk of sarcopenia, potentially due to its anti-inflammatory properties. The objective of this study was to evaluate the association between the Dietary Inflammatory Index (DII) and the Dietary Inflammatory Score (DIS) with sarcopenia in an Iranian population.

methodsIn the present study, 80 participants with sarcopenia were included in the case group, and 80 non-sarcopenia participants were included in the control group, matched by gender. Sarcopenia was diagnosed according to the Asian Working Group on Sarcopenia (AWGS) guidelines. Additionally, dietary data obtained from a food frequency questionnaire were used to calculate participants' DIS and DII scores. The association between the DII and DIS and the odds ratio of sarcopenia was assessed by logistic regression in both crude and adjusted models.

resultsIn the crude model, the odds of sarcopenia were significantly higher for each unit increase in DIS and DII scores (DIS: odds ratio (OR) = 1.221, 95% confidence interval (CI): 1.128-1.322; DII: OR = 1.271, 95% CI: 1.041-1.553). After adjusting for age, energy, and protein intake, higher odds of sarcopenia were observed for each unit increase in DIS score (OR = 1.129, 95% CI: 1.004-1.268). Similarly, higher odds of sarcopenia were seen for each unit increase in DII score after adjusting for potential confounders (OR = 1.269, 95% CI: 1.032-1.561).

conclusionsIn conclusion, this study found that greater adherence to the DII and DIS was associated with higher odds of sarcopenia in older adults. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

DietInflammationSarcopeniaAgedCase-Control StudiesFemaleHumansIranLogistic ModelsMaleMiddle AgedOdds RatioRisk FactorsDietary inflammatory indexInflammationSarcopenia

Identifiers

PMID40450377
PMCPMC12125811

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.