Evidence mapPaperPMID 40450677Full record

ArticleVeterinary medicine and science2025

Effect of High Fructose Corn Syrup and Citric Acid in Broiler Diets on Performance, Gut pH, Immunity, Antioxidant Status and Some Blood Parameters.

Gökhan Şen, Ali Karapinar, Mehmet Naci Oktay, Miyase Çinar, Mehmet Başalan

Abstract read
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gökhan ŞenDepartment of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Kırıkkale University, Kirikkale, Turkey.ORCID 0000-0001-6222-6986
Ali KarapinarDepartment of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Kırıkkale University, Kirikkale, Turkey.
Mehmet Naci OktayDepartment of Animal Breeding and Husbandry, Faculty of Veterinary Medicine, Kırıkkale University, Kirikkale, Turkey.
Miyase ÇinarDepartment of Biochemistry, Faculty of Veterinary Medicine, Kırıkkale University, Kirikkale, Turkey.
Mehmet BaşalanDepartment of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Kırıkkale University, Kirikkale, Turkey.

Funding

Kırıkkale University Scientific Research Coordination Unit
6 · The paper itself

Abstract

The objective of this study was to determine the effect of high fructose corn syrup (HFCS) and citric acid (CA) in broiler diets on performance, gut pH, immunity, antioxidant status and some blood parameters. A total of 120 Ross 308 chicks at the age of 0 days were divided into 4 groups with 3 subgroups of 10 chicks each: control (CON), 50 mg/kg HFCS, 30 mg/kg CA and 50 mg/kg HFCS + 30 mg/kg CA (HFCS + CA). It was determined that body weight gain (BWG) was highest in the CA group and was similar to the CON group, whereas it was lower in the HFCS + CA group than other groups (p < 0.05). The feed conversion rates of the CA and the CON groups were similar and lower than the others (p < 0.05). Carcass weights and ratios increased in the CA group (p < 0.05). There were significant differences between the weights of liver and pancreas of groups (p < 0.05). Serum high-density lipoprotein (HDL)-CHO and GLU levels increased in the HFCS + CA group (p < 0.05). Serum total cholesterol (TCHO) level in the HFCS group was similar to the CON group and lower than the other groups (p < 0.05). Serum tumour necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) values were determined to be highest in the HFCS group and different from the CON group (p < 0.05). It was observed that HFCS negatively affected performance, whereas CA positively affected. HFCS + CA increased serum TCHO and HDL-CHO levels and CA led to an increasing trend in total antioxidant status (TAS) level. Although HFCS had a positive effect on TNF-α and IL-1β, similar of immunoglobulin G (IgG) and immunoglobulin M (IgM) levels between groups was observed.

Indexed as

AntioxidantsChickensCitric AcidHigh Fructose Corn SyrupAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsDietDietary SupplementsGastrointestinal TractHydrogen-Ion ConcentrationMaleRandom AllocationAntioxidantsCitric AcidHigh Fructose Corn Syrupblood parametersbroilercitric acidfructoseperformancesyrup

Identifiers

PMID40450677
PMCPMC12126997

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.