Evidence map›Paper›PMID 40451787›Full record

ArticleThe FEBS journal2025

Lipid regulation of adenylyl cyclase Rv1625c from Mycobacterium tuberculosis by its membrane-domain receptor.

Anita Charlotte Friderun Schultz, Marius Landau, Andrei N Lupas, Joachim Erdmann Schultz

Abstract read
In one paragraph

Article in The FEBS journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anita Charlotte Friderun SchultzMax-Planck-Institute für Biologie, Tübingen, Germany.
Marius LandauMax-Planck-Institute für Biologie, Tübingen, Germany.
Andrei N LupasMax-Planck-Institute für Biologie, Tübingen, Germany.
Joachim Erdmann SchultzMax-Planck-Institute für Biologie, Tübingen, Germany.ORCID https://orcid.org/0000-0002-1985-4853

Funding

Deutsche Forschungsgemeinschaft Schu275/45Max-Planck-Gesellschaft
6 · The paper itself

Abstract

The regulation of mammalian adenylyl cyclases by G-protein-coupled receptors and the Gsα subunit of trimeric G-proteins has been extensively studied, whereas little is known about the regulation of their closely related bacterial cyclases. Here, we focused on the regulation of the adenylyl cyclase Rv1625c from Mycobacterium tuberculosis H37Rv. Rv1625c is a progenitor of mammalian congeners. Exclusively C

Indexed as

Adenylyl CyclasesBacterial ProteinsMycobacterium tuberculosisAdenosine TriphosphateMagnesiumManganeseProtein DomainsSignal TransductionAdenosine TriphosphateAdenylyl CyclasesBacterial ProteinsMagnesiumManganeseadenylyl cyclaselipid receptormycobacteriumoleic acidregulation

Identifiers

PMID40451787
PMCPMC12505454

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.