ArticleEnvironmental health and preventive medicine2025
Physical activity and risk of sarcopenia in 6500 community-dwelling Japanese people aged 40-74 years: an 8-year follow-up study.
Article in Environmental health and preventive medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Habitual physical activity and sarcopenia: a systematic review and meta-analysis of prospective cohort studies.Journal of global health · 2026Pooled it
- Dietary protein intake, animal-to-plant protein ratio and risk of sarcopenia in community-dwelling adults: a 9-year follow-up study.Public health nutrition · 2026Article
- Article
- The relationship between sarcopenic obesity and cognitive functionality among inpatients with stable schizophrenia.PloS one · 2025Article
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16 authors.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimThe association between physical activity (PA) and sarcopenia has mostly been investigated in older people, with few studies focused on earlier life stages. The present study aimed to determine whether higher PA levels are associated with a lower sarcopenia risk in middle-aged and early older people.
methodsThis was an 8-year follow-up study. Participants were 6,500 community-dwelling adults aged 40-74 years who participated in the baseline questionnaire survey conducted in 2011-2014 in Japan. Levels of total and leisure-time PAs at baseline were assessed using validated metabolic equivalent scores. Multi-frequency bioelectrical impedance analysis and handgrip strength measurement were performed in 2021-2022, and participants with low height-adjusted appendicular lean mass (<20th percentile) and low grip strength were diagnosed as having sarcopenia (outcome). Covariates were demographics, body size, lifestyle, and disease history at baseline.
resultsThe prevalence of sarcopenia was 137/2926 (4.7%) for men and 127/3574 (3.6%) for women. Higher total PA levels were associated with lower odds of sarcopenia (P for trend = 0.0278), with the second highest group having a significantly lower OR (0.51) than the lowest group (reference) in women, but not in men. Regarding leisure-time PA, those engaged in leisure-time vigorous PA had a lower OR of sarcopenia than those who did not (OR = 0.67, P = 0.0625).
conclusionHigher levels of total PA are associated with a lower risk of sarcopenia in women but not in men, suggesting a sex difference in this association. In addition, high levels of vigorous leisure-time PA may be effective for preventing sarcopenia.
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