Evidence map›Paper›PMID 40451983›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Multi-Organ metabolic profiling with [

Qiaoke Ma, Jinhui Yang, Xuan Guo, Wenna Mu, Yongxiang Tang, Jian Li, Shuo Hu

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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiaoke Ma *Department of Nuclear Medicine, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha City, Hunan Province, 410008, P.R. China.
Jinhui Yang *Department of Nuclear Medicine, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha City, Hunan Province, 410008, P.R. China.
Xuan GuoDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha City, Hunan Province, 410008, P.R. China.
Wenna MuDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha City, Hunan Province, 410008, P.R. China.
Yongxiang TangDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha City, Hunan Province, 410008, P.R. China.
Jian LiDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha City, Hunan Province, 410008, P.R. China. lijian19850108@163.com.
Shuo HuDepartment of Nuclear Medicine, Xiangya Hospital, Central South University, No.87 Xiangya Road, Changsha City, Hunan Province, 410008, P.R. China. hushuo2018@163.com.ORCID 0000-0003-0998-8943

Funding

Clinical Research Foundation of the National Clinical Research Center for Geriatric Diseases (XIANGYA) 2020LNJJ01Key Program of Ministry of Industry and Information Technology of China CEIEC-2022-ZM02-0219National Natural Science Foundation of China 82272045Natural Science Foundation of Hunan Province 2022JJ30936
6 · The paper itself

Abstract

purposeTo develop and validate a novel nomogram combining multi-organ PET metabolic metrics for major pathological response (MPR) prediction in resectable non-small cell lung cancer (rNSCLC) patients receiving neoadjuvant immunochemotherapy.

methodsThis retrospective cohort included rNSCLC patients who underwent baseline [

resultsAmong 115 patients (MPR rate: 63.5%, n = 73), five metabolic parameters emerged as predictive biomarkers for MPR: Spleen_SUV

conclusionsThis first-reported multi-organ metabolic nomogram noninvasively predicts MPR in rNSCLC patients receiving neoadjuvant immunochemotherapy, outperforming conventional tumor-centric approaches. By quantifying systemic host-tumor metabolic crosstalk, this tool could help guide personalized therapeutic decisions while mitigating treatment-related risks, representing a paradigm shift towards precision immuno-oncology management.

Indexed as

Carcinoma, Non-Small-Cell LungFluorodeoxyglucose F18ImmunotherapyLung NeoplasmsNeoadjuvant TherapyPositron Emission Tomography Computed TomographyAgedFemaleHumansMaleMiddle AgedNomogramsRetrospective StudiesTreatment OutcomeFluorodeoxyglucose F18[18F]F-FDG PET/CTMajor pathological responseMulti-organ metabolismNeoadjuvant immunochemotherapyNomogramNon-small cell lung cancer

Identifiers

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.