Evidence map›Paper›PMID 40451993›Full record

ReviewInternal and emergency medicine2025

Empowering the vulnerable in internal medicine: a narrative review on physical exercise as a tool to tackle frailty.

Marco Vincenzo Lenti, Alice Silvia Brera, Antonio Di Sabatino, Gino Roberto Corazza

Abstract readReview
PubMed Publisher
In one paragraph

Review in Internal and emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marco Vincenzo Lenti *Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Alice Silvia Brera *First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Viale Golgi 19, 27100, Pavia, Italy.
Antonio Di SabatinoDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy.
Gino Roberto CorazzaDepartment of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy. gr.corazza@smatteo.pv.it.ORCID 0000-0001-9532-0573

Funding

Fondazione IRCCS Policlinico San Matteo Progetto di Ricerca Corrente 2017
6 · The paper itself

Abstract

Frailty is an increasingly recognized issue in internal medicine, which develops as a consequence of age-related decline in multiple physiological systems, underlying a vulnerable state of health due to poor homeostatic resources. Rapid muscle exhaustion, muscle weakness, dynapaenia, and sarcopenia are common features of frail patients. Indeed, frailty is associated with an increased risk of hospitalization and mortality, and it may be reversed through physical activity and other lifestyle interventions, so to prevent the decline of physical and mental functioning. We herein sought to describe in a narrative fashion the current knowledge about frailty and physical exercise, focusing only on original articles in which frailty was detected and quantified according to international, validated scales or other methods. We will finally discuss future perspectives with regard to the applications of physical exercise in the prevention or treatment of frailty.

Indexed as

ExerciseFrailtyAgedAged, 80 and overFrail ElderlyHumansInternal MedicineAgeingMultimorbidityOlder adultsSarcopenia

Identifiers

PMID40451993

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.