Evidence map›Paper›PMID 40451998›Full record

ArticleDigestive diseases and sciences2025

Risk of Post-polypectomy Bleeding After Colorectal Endoscopic Mucosal Resection in Patients with Chronic Kidney Disease: A Propensity-Matched Analysis of the US Collaborative Network.

Azizullah Beran, Khaled Elfert, Feenalie N Patel, Mouhand Mohamed, Daryl Ramai, Almaza Albakri, Nasir Saleem, Faisal Kamal, Andrew Canakis, Khaled Srour and 5 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Azizullah BeranDivision of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA.
Khaled ElfertDivision of Gastroenterology and Hepatology, West Virginia University School of Medicine, Morgantown, WV, USA.
Feenalie N PatelDivision of Gastroenterology and Hepatology, Houston Methodist Hospital, Houston, TX, USA.
Mouhand MohamedDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Daryl RamaiDivision of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Boston, MA, USA.
Almaza AlbakriDepartment of Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Nasir SaleemDivision of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA.
Faisal KamalDivision of Thomas Jefferson University, Philadelphia, PA, USA.
Andrew CanakisDivision of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Khaled SrourDivision of Nephrology, AdventHealth Medical Group, Orlando, FL, USA.
Danial H ShaikhDivision of Gastroenterology, Geisinger Health System, Danville, PA, USA.
Shyam ThakkarDivision of Gastroenterology and Hepatology, Houston Methodist Hospital, Houston, TX, USA.
Douglas K RexDivision of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA.
Indira Bhavsar-BurkeDivision of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, USA.
John J GuardiolaDivision of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA. joguar@iu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies evaluating the risk of post-polypectomy bleeding (PPB) after colorectal endoscopic mucosal resection (EMR) in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) are limited.

methodsThis retrospective cohort study utilized the U.S. Collaborative Network to assess the risk of PPB after colorectal EMR in patients with CKD compared to controls. Using one-to-one propensity score matching (PSM), the primary outcome measured was PPB within 30 days after colorectal EMR. The PPB risk was further stratified by CKD severity: non-advanced CKD and advanced CKD.

resultsAfter PSM, each cohort included 9,196 patients. Overall, CKD was associated with increased risk of PPB following colorectal EMR (5.4% vs. 3.8%, odds ratio [OR] 1.44, 95% confidence interval [CI] 1.25-1.66, p < 0.001). The PPB risk was significantly higher in patients with advanced CKD (8.1% vs. 4%, OR 2.09, 95% CI 1.65-2.65, p < 0.001), while those with non-advanced CKD showed modest increase in risk of PPB (4.7% vs. 4%, OR 1.20, 95% CI 1.01-1.41, p = 0.03).

conclusionPatients with CKD had higher risk of PPB than patients without CKD. The PPB risk was notably increased in patients with advanced CKD. Optimizing patients with CKD, especially advanced CKD, before colorectal EMR and monitoring for post-procedure bleeding remains important.

Indexed as

Colonic PolypsColonoscopyEndoscopic Mucosal ResectionGastrointestinal HemorrhagePostoperative HemorrhageRenal Insufficiency, ChronicAgedFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesRisk FactorsUnited StatesChronic kidney diseaseColorectal polypsDialysisEndoscopic mucosal resectionPost-polypectomy bleeding

Identifiers

PMID40451998
PMCPMC12411577

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.