Evidence mapPaperPMID 40452196Full record

Trial reportJournal of musculoskeletal & neuronal interactions2025

Efficacy of Atorvastatin Against Venous Thromboembolism After Total Hip Arthroplasty.

Huajiang Liu, Yi Kang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of musculoskeletal & neuronal interactions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The role of statins in mitigating venous thromboembolism incidence and severity.Research and practice in thrombosis and haemostasis · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Huajiang LiuOrthopedics and Traumatology Department II, Jiangxi Province Hospital of Integrated Chinese and Western Medicine, Nanchang, Jiangxi, China.
Yi KangOrthopedics and Traumatology Department II, Jiangxi Province Hospital of Integrated Chinese and Western Medicine, Nanchang, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe examined the effect of atorvastatin on the prevention and management of venous thromboembolism (VTE) after total hip arthroplasty (THA).

methodsA total of 300 patients were equally assigned to a treatment group and a control group. The treatment group received oral atorvastatin calcium tablets (20 mg/day) starting on the first day after surgery. The incidence of deep vein thrombosis, pulmonary embolism, incision hemorrhage, postoperative infection, and incision ecchymosis were evaluated in both groups. Additionally, hemoglobin levels, hematocrit, visual analog scale (VAS) pain scores, Harris hip scores, and Harris grading were compared between the two groups.

resultsThe incidence of deep vein thrombosis, pulmonary embolism, incision hemorrhage, postoperative infection, and incision ecchymosis was significantly lower in the treatment group after atorvastatin intervention (P < 0.05 vs. control group). The hemoglobin levels, hematocrits, and VAS scores in the treatment group were significantly lower on days 1, 3, 7, and 14 after surgery (P < 0.05 vs. control group). The Harris hip scores and the number of patients with excellent Harris grading were significantly higher in the treatment group (P < 0.05 vs. control group).

conclusionAtorvastatin is effective in preventing VTE after THA and in improving postoperative joint function.

Indexed as

Arthroplasty, Replacement, HipAtorvastatinHydroxymethylglutaryl-CoA Reductase InhibitorsPostoperative ComplicationsVenous ThromboembolismAgedFemaleHumansMaleMiddle AgedTreatment OutcomeAtorvastatinHydroxymethylglutaryl-CoA Reductase InhibitorsAtorvastatinTotal Hip ArthroplastyVenous Thromboembolism

Identifiers

PMID40452196
PMCPMC12131077

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.