Evidence map›Paper›PMID 40453145›Full record

Trial reportBlood neoplasia2025

Adult leukemia in Florida 2010-2019: diverse, aging population as an indicator for the United States.

Ming S Lee, Rebecca E Kaiser, Christopher D Armstrong, David B Dukenik, Nancy S Elliott, Raymond R Balise, Justin M Watts, Mikkael A Sekeres, Erin N Kobetz, Justin Taylor

Abstract readClinical Trial
In one paragraph

Trial report in Blood neoplasia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ming S LeeSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL.
Rebecca E KaiserDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL.
Christopher D ArmstrongHuman Genetics Program, University of Miami Miller School of Medicine, Miami, FL.
David B DukenikSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL.
Nancy S ElliottSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL.
Raymond R BaliseDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL.
Justin M WattsLeukemia Service, Division of Hematology, University of Miami Miller School of Medicine, Miami, FL.
Mikkael A SekeresLeukemia Service, Division of Hematology, University of Miami Miller School of Medicine, Miami, FL.
Erin N KobetzSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL.
Justin TaylorSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL.

Funding

Tumor Biology Research ProgramP30CA240139 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Stephen D. Nimer · 2019 to 2026
$24.1M
The role of XPO1 in nuclear export of RNAR35GM151109 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Justin Taylor · 2023 to 2026
$1.5M
NCI NIH HHS P30 CA240139NIGMS NIH HHS R35 GM151109
6 · The paper itself

Abstract

According to recent data released by the National Cancer Institute, Florida has the highest incidence of adult leukemia in the United States. There is limited population-based research on aging and sociodemographic disparities associated with leukemia in Florida, which can have a national impact on the assessment of leukemia burden. Using geocoded cancer data from the Florida Cancer Data System and population data from the US Census, this study evaluated socioeconomic and regional disparities associated with leukemia and found that leukemia disparities by race/ethnicity and rurality exist in Florida. The non-Hispanic White population had the highest incidence rates for most subtypes of leukemia, whereas the non-Hispanic Black population had the highest odds of dying from leukemia. Rural counties and urban neighborhoods with lower socioeconomic status were associated with higher mortality odds for leukemia. Leukemia-treating physician numbers were mismatched in regions in which patients with leukemia exhibit higher incidence and mortality odds. These results suggest that leukemia incidence rate in Florida is likely to remain among the highest in the United States due to population aging; however, physician shortages may exacerbate disparities and limit care in rural areas. Florida demographically looks like what the entire US population may be in the future and is therefore an indicator of the coming needs in the United States for increased leukemia diagnosis, treatment, and survivorship care. Larger national and international studies can build on this study by applying our methodology on a larger scale and can also be applied to other hematologic malignancies and other cancer types.

Identifiers

PMID40453145
PMCPMC12067876

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.