ArticleInternational journal of general medicine2025
Correlation Between Serum D-Dimer, NLR, and CRP/ALB in Patients with Acute Ischemic Stroke.
Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Cumulative inflammatory, coagulation, and metabolic abnormalities predict poor 90-day functional outcome after endovascular thrombectomy for large-vessel occlusion acute ischemic stroke.Frontiers in neurology · 2026Article
- Systemic inflammatory biomarkers CAR and IL-6: correlation with neurological deficit and short-term prognosis of intracerebral hemorrhage.Frontiers in neurology · 2026Article
- C-reactive protein-to-albumin ratio predicts intensive care admission and disease severity in autoimmune encephalitis.Frontiers in immunology · 2026Article
- Serum Biomarkers in Acute Ischemic Stroke: Clinical Applications and Emerging Insights.Journal of clinical medicine · 2025Review
- Novel Computed Tomography Perfusion and Laboratory Indices as Predictors of Long-Term Outcome and Survival in Acute Ischemic Stroke.Neurology international · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study examines the association between serum D-dimer (D-D), neutrophil-to-lymphocyte ratio (NLR), C-reactive protein to albumin ratio (CRP/ALB), and the prognosis of intravenous thrombolysis in patients with acute ischemic stroke (AIS). Methods: Ninety AIS patients admitted from June 2021 to October 2023 were included and divided into poor prognosis (29 cases) and good prognosis groups (61 cases) based on 90-day follow-up modified Rankin Scale (mRS) scores. Binary logistic regression identified prognostic factors, while ROC analysis evaluated the predictive efficacy of D-D, NLR, and CRP/ALB. Correlations among these markers were also analyzed. Results: Binary logistic regression showed that age, D-D, ALB, CRP/ALB, neutrophil count, lymphocyte count, and NLR were significant prognostic risk factors (P < 0.05). ROC analysis yielded AUC values of 0.683 for D-D, 0.769 for NLR, and 0.728 for CRP/ALB, with combined AUC reaching 0.803. Sensitivity and specificity were 96.6%/39.3% for D-D, 100.0%/68.9% for NLR, and 100.0%/45.9% for CRP/ALB. Spearman correlation analysis revealed positive correlations among D-D, NLR, and CRP/ALB (r = 0.367, 0.482, 0.462, p < 0.05). Conclusion: Age, D-D, ALB, CRP/ALB, neutrophil count, lymphocyte count, and NLR are significant prognostic factors for intravenous thrombolysis in AIS patients. D-D, NLR, and CRP/ALB are effective indicators for predicting prognosis, with combined prediction showing greater efficacy.
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